Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer

Abstract G-quadruplex (G4) structures are considered a promising therapeutic target in cancer. Since Ayurveda, Piperine has been known for its medicinal properties. Piperine shows anticancer properties by stabilizing the G4 motif present upstream of the c-myc gene. This gene belongs to a group of pr...

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Autores principales: Nirali Pandya, Amit Kumar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9988fb2e58534a5a94b4c20cd7bfd0a7
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