Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

<h4>Objective</h4>Many patients with rheumatoid arthritis (RA) benefit from tumor necrosis factor-α blocking treatment (anti-TNF), but about one third do not respond. The objective of this study was to replicate and extend previously found associations between anti-TNF treatment response...

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Autores principales: Jacob Sode, Ulla Vogel, Steffen Bank, Paal Skytt Andersen, Marianne Kragh Thomsen, Merete Lund Hetland, Henning Locht, Niels H H Heegaard, Vibeke Andersen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/99897076b05c4c918622565bb3bb7063
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