Molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1

C5-glyceryl-methylcytosine is a DNA modification that plays a role in the regulation of green alga photosynthesis and is catalysed by CMD1, using vitamin C (VC) as a co-substrate. Here, the authors provide insights into the catalytic mechanism of CMD1 by determining the crystal structures of apo CMD...

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Autores principales: Wenjing Li, Tianlong Zhang, Mingliang Sun, Yu Shi, Xiao-Jie Zhang, Guo-Liang Xu, Jianping Ding
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/998b20601bc74f88a0e1304c7a59a690
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