Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies

Transcriptional regulation is necessary for maintaining long-term memories (LTM) but the mechanistic details are not completely defined. Here the authors identify transcriptional machinery and histone modifiers required for LTM maintenance inDrosophilaand show that transcriptional regulation for LTM...

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Autores principales: Yukinori Hirano, Kunio Ihara, Tomoko Masuda, Takuya Yamamoto, Ikuko Iwata, Aya Takahashi, Hiroko Awata, Naosuke Nakamura, Mai Takakura, Yusuke Suzuki, Junjiro Horiuchi, Hiroyuki Okuno, Minoru Saitoe
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/998cbddbf27b4ae0b812163baeb13eb6
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spelling oai:doaj.org-article:998cbddbf27b4ae0b812163baeb13eb62021-12-02T17:32:07ZShifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies10.1038/ncomms134712041-1723https://doaj.org/article/998cbddbf27b4ae0b812163baeb13eb62016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13471https://doaj.org/toc/2041-1723Transcriptional regulation is necessary for maintaining long-term memories (LTM) but the mechanistic details are not completely defined. Here the authors identify transcriptional machinery and histone modifiers required for LTM maintenance inDrosophilaand show that transcriptional regulation for LTM maintenance is distinct from that for LTM formation.Yukinori HiranoKunio IharaTomoko MasudaTakuya YamamotoIkuko IwataAya TakahashiHiroko AwataNaosuke NakamuraMai TakakuraYusuke SuzukiJunjiro HoriuchiHiroyuki OkunoMinoru SaitoeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yukinori Hirano
Kunio Ihara
Tomoko Masuda
Takuya Yamamoto
Ikuko Iwata
Aya Takahashi
Hiroko Awata
Naosuke Nakamura
Mai Takakura
Yusuke Suzuki
Junjiro Horiuchi
Hiroyuki Okuno
Minoru Saitoe
Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
description Transcriptional regulation is necessary for maintaining long-term memories (LTM) but the mechanistic details are not completely defined. Here the authors identify transcriptional machinery and histone modifiers required for LTM maintenance inDrosophilaand show that transcriptional regulation for LTM maintenance is distinct from that for LTM formation.
format article
author Yukinori Hirano
Kunio Ihara
Tomoko Masuda
Takuya Yamamoto
Ikuko Iwata
Aya Takahashi
Hiroko Awata
Naosuke Nakamura
Mai Takakura
Yusuke Suzuki
Junjiro Horiuchi
Hiroyuki Okuno
Minoru Saitoe
author_facet Yukinori Hirano
Kunio Ihara
Tomoko Masuda
Takuya Yamamoto
Ikuko Iwata
Aya Takahashi
Hiroko Awata
Naosuke Nakamura
Mai Takakura
Yusuke Suzuki
Junjiro Horiuchi
Hiroyuki Okuno
Minoru Saitoe
author_sort Yukinori Hirano
title Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
title_short Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
title_full Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
title_fullStr Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
title_full_unstemmed Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
title_sort shifting transcriptional machinery is required for long-term memory maintenance and modification in drosophila mushroom bodies
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/998cbddbf27b4ae0b812163baeb13eb6
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