Coagulation factor X interaction with macrophages through its N-glycans protects it from a rapid clearance.

Factor X (FX), a plasma glycoprotein playing a central role in coagulation has a long circulatory half-life compared to closely related coagulation factors. The activation peptide of FX has been shown to influence its clearance with two N-glycans as key determinants of FX's relatively long surv...

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Autores principales: Mohamad Kurdi, Ghislaine Cherel, Peter J Lenting, Cécile V Denis, Olivier D Christophe
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/998d4d7e17784cbd9818af40362ee833
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