Evaluation of antithrombotic activity of thrombin DNA aptamers by a murine thrombosis model.
Aptamers are nucleic acid based molecular recognition elements with a high potential for the theranostics. Some of the aptamers are under development for therapeutic applications as promising antithrombotic agents; and G-quadruplex DNA aptamers, which directly inhibit the thrombin activity, are amon...
Guardado en:
Autores principales: | Elena Zavyalova, Nadezhda Samoylenkova, Alexander Revishchin, Andrey Golovin, Galina Pavlova, Alexey Kopylov |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/999b92fe1837498d9e52791d049d878b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin
por: Asif Iqbal, et al.
Publicado: (2017) -
Identification of the Antithrombotic Mechanism of Leonurine in Adrenalin Hydrochloride-Induced Thrombosis in Zebrafish via Regulating Oxidative Stress and Coagulation Cascade
por: Li Liao, et al.
Publicado: (2021) -
New synthetic thrombin inhibitors: molecular design and experimental verification.
por: Elena I Sinauridze, et al.
Publicado: (2011) -
DNA aptamers against the Lup an 1 food allergen.
por: Pedro Nadal, et al.
Publicado: (2012) -
DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis
por: Nirit Mor-Vaknin, et al.
Publicado: (2017)