Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha

HCMV is a herpesvirus that infects a large percentage of the adult population and causes significant levels of disease in immunocompromised individuals and birth defects in the developing fetus. The virus encodes a complex protein machinery that coordinates infection of different cell types in the...

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Autores principales:	Jing Liu, Adam Vanarsdall, Dong-Hua Chen, Andrea Chin, David Johnson, Theodore S. Jardetzky
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/99a3ab6028954f238a25604e90e9a233
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spelling	oai:doaj.org-article:99a3ab6028954f238a25604e90e9a2332021-11-03T21:52:35ZCryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha2150-751110.1128/mBio.02625-21https://doaj.org/article/99a3ab6028954f238a25604e90e9a2332021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02625-21https://doaj.org/toc/2150-7511 HCMV is a herpesvirus that infects a large percentage of the adult population and causes significant levels of disease in immunocompromised individuals and birth defects in the developing fetus. The virus encodes a complex protein machinery that coordinates infection of different cell types in the body, including a trimer formed of gH, gL, and gO subunits.Jing LiuAdam VanarsdallDong-Hua ChenAndrea ChinDavid JohnsonTheodore S. JardetzkyAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Jing Liu Adam Vanarsdall Dong-Hua Chen Andrea Chin David Johnson Theodore S. Jardetzky Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
description	HCMV is a herpesvirus that infects a large percentage of the adult population and causes significant levels of disease in immunocompromised individuals and birth defects in the developing fetus. The virus encodes a complex protein machinery that coordinates infection of different cell types in the body, including a trimer formed of gH, gL, and gO subunits.
format	article
author	Jing Liu Adam Vanarsdall Dong-Hua Chen Andrea Chin David Johnson Theodore S. Jardetzky
author_facet	Jing Liu Adam Vanarsdall Dong-Hua Chen Andrea Chin David Johnson Theodore S. Jardetzky
author_sort	Jing Liu
title	Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
title_short	Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
title_full	Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
title_fullStr	Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
title_full_unstemmed	Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
title_sort	cryo-electron microscopy structure and interactions of the human cytomegalovirus ghglgo trimer with platelet-derived growth factor receptor alpha
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/99a3ab6028954f238a25604e90e9a233
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Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha

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