The cryo-EM structure of the SNX–BAR Mvp1 tetramer

SNX-BAR proteins are a family of PX and BAR domain-containing proteins with pivotal roles in trafficking processes. Here authors present the cryo-EM structure of the full-length fungal SNX-BAR Mvp1, which is an autoinhibited tetramer and provides critical insight into SNX-BAR function and regulation...

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Autores principales: Dapeng Sun, Natalia V. Varlakhanova, Bryan A. Tornabene, Rajesh Ramachandran, Peijun Zhang, Marijn G. J. Ford
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/99a8ac44d31b4943bbb26fff79c4ed3a
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spelling oai:doaj.org-article:99a8ac44d31b4943bbb26fff79c4ed3a2021-12-02T14:41:24ZThe cryo-EM structure of the SNX–BAR Mvp1 tetramer10.1038/s41467-020-15110-52041-1723https://doaj.org/article/99a8ac44d31b4943bbb26fff79c4ed3a2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15110-5https://doaj.org/toc/2041-1723SNX-BAR proteins are a family of PX and BAR domain-containing proteins with pivotal roles in trafficking processes. Here authors present the cryo-EM structure of the full-length fungal SNX-BAR Mvp1, which is an autoinhibited tetramer and provides critical insight into SNX-BAR function and regulation.Dapeng SunNatalia V. VarlakhanovaBryan A. TornabeneRajesh RamachandranPeijun ZhangMarijn G. J. FordNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dapeng Sun
Natalia V. Varlakhanova
Bryan A. Tornabene
Rajesh Ramachandran
Peijun Zhang
Marijn G. J. Ford
The cryo-EM structure of the SNX–BAR Mvp1 tetramer
description SNX-BAR proteins are a family of PX and BAR domain-containing proteins with pivotal roles in trafficking processes. Here authors present the cryo-EM structure of the full-length fungal SNX-BAR Mvp1, which is an autoinhibited tetramer and provides critical insight into SNX-BAR function and regulation.
format article
author Dapeng Sun
Natalia V. Varlakhanova
Bryan A. Tornabene
Rajesh Ramachandran
Peijun Zhang
Marijn G. J. Ford
author_facet Dapeng Sun
Natalia V. Varlakhanova
Bryan A. Tornabene
Rajesh Ramachandran
Peijun Zhang
Marijn G. J. Ford
author_sort Dapeng Sun
title The cryo-EM structure of the SNX–BAR Mvp1 tetramer
title_short The cryo-EM structure of the SNX–BAR Mvp1 tetramer
title_full The cryo-EM structure of the SNX–BAR Mvp1 tetramer
title_fullStr The cryo-EM structure of the SNX–BAR Mvp1 tetramer
title_full_unstemmed The cryo-EM structure of the SNX–BAR Mvp1 tetramer
title_sort cryo-em structure of the snx–bar mvp1 tetramer
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/99a8ac44d31b4943bbb26fff79c4ed3a
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