Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2

Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2

Haematopoiesis and the generation of lymphoid cell subsets are controlled by delicate genetic programs enforced via epigenetic regulation. Here the authors show that Pcid2 interacts with ZNHIT1, a component of the SRCAP chromatin remodelling complex, to critically modulate the differentiation of mul...

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Autores principales: Buqing Ye, Benyu Liu, Liuliu Yang, Guanling Huang, Lu Hao, Pengyan Xia, Shuo Wang, Ying Du, Xiwen Qin, Pingping Zhu, Jiayi Wu, Nobuo Sakaguchi, Junyan Zhang, Zusen Fan
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/99b4f3c177f8426eb90c65ef0672f322
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spelling oai:doaj.org-article:99b4f3c177f8426eb90c65ef0672f3222021-12-02T17:06:19ZSuppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid210.1038/s41467-017-01788-72041-1723https://doaj.org/article/99b4f3c177f8426eb90c65ef0672f3222017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01788-7https://doaj.org/toc/2041-1723Haematopoiesis and the generation of lymphoid cell subsets are controlled by delicate genetic programs enforced via epigenetic regulation. Here the authors show that Pcid2 interacts with ZNHIT1, a component of the SRCAP chromatin remodelling complex, to critically modulate the differentiation of multipotent progenitors.Buqing YeBenyu LiuLiuliu YangGuanling HuangLu HaoPengyan XiaShuo WangYing DuXiwen QinPingping ZhuJiayi WuNobuo SakaguchiJunyan ZhangZusen FanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Buqing Ye
Benyu Liu
Liuliu Yang
Guanling Huang
Lu Hao
Pengyan Xia
Shuo Wang
Ying Du
Xiwen Qin
Pingping Zhu
Jiayi Wu
Nobuo Sakaguchi
Junyan Zhang
Zusen Fan
Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
description Haematopoiesis and the generation of lymphoid cell subsets are controlled by delicate genetic programs enforced via epigenetic regulation. Here the authors show that Pcid2 interacts with ZNHIT1, a component of the SRCAP chromatin remodelling complex, to critically modulate the differentiation of multipotent progenitors.
format article
author Buqing Ye
Benyu Liu
Liuliu Yang
Guanling Huang
Lu Hao
Pengyan Xia
Shuo Wang
Ying Du
Xiwen Qin
Pingping Zhu
Jiayi Wu
Nobuo Sakaguchi
Junyan Zhang
Zusen Fan
author_facet Buqing Ye
Benyu Liu
Liuliu Yang
Guanling Huang
Lu Hao
Pengyan Xia
Shuo Wang
Ying Du
Xiwen Qin
Pingping Zhu
Jiayi Wu
Nobuo Sakaguchi
Junyan Zhang
Zusen Fan
author_sort Buqing Ye
title Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
title_short Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
title_full Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
title_fullStr Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
title_full_unstemmed Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2
title_sort suppression of srcap chromatin remodelling complex and restriction of lymphoid lineage commitment by pcid2
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/99b4f3c177f8426eb90c65ef0672f322
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