Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes

Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes

Psoriasis is a chronic inflammatory skin condition characterized by abnormal keratinocyte proliferation and differentiation that is accompanied with dysregulated immune response and abnormal vascularization. Devil’s claw (<i>Harpagophytum procumbens</i> (Burch.) DC. ex Meisn.) tubers ext...

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Autores principales: Ivanka K. Koycheva, Liliya V. Mihaylova, Monika N. Todorova, Zhivka P. Balcheva-Sivenova, Kalina Alipieva, Claudio Ferrante, Giustino Orlando, Milen I. Georgiev
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
psoriasis
keratinocytes
inflammation
verbascoside
leucosceptoside A
devil’s claw
Organic chemistry
QD241-441
Acceso en línea:https://doaj.org/article/99b65710ec314300a165d3fbc4a59782
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