Locally anchoring enzymes to tissues via extracellular glycan recognition

The use of enzymes as drugs requires that they persist within target tissues over therapeutically relevant time frames. Here the authors use a galectin-3 fusion to anchor enzymes at injection sites for up to 14 days.

Saved in:
Bibliographic Details
Main Authors: Shaheen A. Farhadi, Evelyn Bracho-Sanchez, Margaret M. Fettis, Dillon T. Seroski, Sabrina L. Freeman, Antonietta Restuccia, Benjamin G. Keselowsky, Gregory A. Hudalla
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/99b77a528cc74b09b0fb7568fbf3a3a5
Tags: Add Tag
No Tags, Be the first to tag this record!