Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs

ABSTRACT Herpes simplex virus 1 (HSV-1) switches between two infection programs, productive (“lytic”) and latent infection. Some HSV-1 microRNAs (miRNAs) have been hypothesized to help control this switch, and yet little is known about regulation of their expression. Using Northern blot analyses, we...

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Auteurs principaux: Dongli Pan, Gang Li, Jenna Morris-Love, Shuyuan Qi, Lei Feng, Max E. Mertens, Igor Jurak, David M. Knipe, Donald M. Coen
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
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Accès en ligne:https://doaj.org/article/99c7849ba22c43728aa9df862ba4edbe
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