Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs

ABSTRACT Herpes simplex virus 1 (HSV-1) switches between two infection programs, productive (“lytic”) and latent infection. Some HSV-1 microRNAs (miRNAs) have been hypothesized to help control this switch, and yet little is known about regulation of their expression. Using Northern blot analyses, we...

Full description

Saved in:
Bibliographic Details
Main Authors: Dongli Pan, Gang Li, Jenna Morris-Love, Shuyuan Qi, Lei Feng, Max E. Mertens, Igor Jurak, David M. Knipe, Donald M. Coen
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Online Access:https://doaj.org/article/99c7849ba22c43728aa9df862ba4edbe
Tags: Add Tag
No Tags, Be the first to tag this record!