Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma

Nodular lymphocyte-predominant Hodgkin lymphoma with IgD+ lymphocyte-predominant (LP) cells is a rare clinical distinct lymphoma subset of B-cell origin. Here the authors show that antigens expressed by Moraxella catarrhalis are recognized by B cell receptors of IgD+ LP cells, suggesting the contrib...

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Autores principales: Lorenz Thurner, Sylvia Hartmann, Natalie Fadle, Evi Regitz, Maria Kemele, Yoo-Jin Kim, Rainer Maria Bohle, Anna Nimmesgern, Lutz von Müller, Volkhard A. J. Kempf, Marc A. Weniger, Frank Neumann, Nadine Schneider, Martine Vornanen, Christer Sundström, Laurence de Leval, Andreas Engert, Dennis A. Eichenauer, Ralf Küppers, Klaus-Dieter Preuss, Martin-Leo Hansmann, Michael Pfreundschuh
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Publicado: Nature Portfolio 2020
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spelling oai:doaj.org-article:99cb03073ee3445083e53f1da680f3692021-12-02T16:49:44ZLymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma10.1038/s41467-020-16375-62041-1723https://doaj.org/article/99cb03073ee3445083e53f1da680f3692020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16375-6https://doaj.org/toc/2041-1723Nodular lymphocyte-predominant Hodgkin lymphoma with IgD+ lymphocyte-predominant (LP) cells is a rare clinical distinct lymphoma subset of B-cell origin. Here the authors show that antigens expressed by Moraxella catarrhalis are recognized by B cell receptors of IgD+ LP cells, suggesting the contribution of chronic antigen stimulation to lymphomagenesis.Lorenz ThurnerSylvia HartmannNatalie FadleEvi RegitzMaria KemeleYoo-Jin KimRainer Maria BohleAnna NimmesgernLutz von MüllerVolkhard A. J. KempfMarc A. WenigerFrank NeumannNadine SchneiderMartine VornanenChrister SundströmLaurence de LevalAndreas EngertDennis A. EichenauerRalf KüppersKlaus-Dieter PreussMartin-Leo HansmannMichael PfreundschuhNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lorenz Thurner
Sylvia Hartmann
Natalie Fadle
Evi Regitz
Maria Kemele
Yoo-Jin Kim
Rainer Maria Bohle
Anna Nimmesgern
Lutz von Müller
Volkhard A. J. Kempf
Marc A. Weniger
Frank Neumann
Nadine Schneider
Martine Vornanen
Christer Sundström
Laurence de Leval
Andreas Engert
Dennis A. Eichenauer
Ralf Küppers
Klaus-Dieter Preuss
Martin-Leo Hansmann
Michael Pfreundschuh
Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
description Nodular lymphocyte-predominant Hodgkin lymphoma with IgD+ lymphocyte-predominant (LP) cells is a rare clinical distinct lymphoma subset of B-cell origin. Here the authors show that antigens expressed by Moraxella catarrhalis are recognized by B cell receptors of IgD+ LP cells, suggesting the contribution of chronic antigen stimulation to lymphomagenesis.
format article
author Lorenz Thurner
Sylvia Hartmann
Natalie Fadle
Evi Regitz
Maria Kemele
Yoo-Jin Kim
Rainer Maria Bohle
Anna Nimmesgern
Lutz von Müller
Volkhard A. J. Kempf
Marc A. Weniger
Frank Neumann
Nadine Schneider
Martine Vornanen
Christer Sundström
Laurence de Leval
Andreas Engert
Dennis A. Eichenauer
Ralf Küppers
Klaus-Dieter Preuss
Martin-Leo Hansmann
Michael Pfreundschuh
author_facet Lorenz Thurner
Sylvia Hartmann
Natalie Fadle
Evi Regitz
Maria Kemele
Yoo-Jin Kim
Rainer Maria Bohle
Anna Nimmesgern
Lutz von Müller
Volkhard A. J. Kempf
Marc A. Weniger
Frank Neumann
Nadine Schneider
Martine Vornanen
Christer Sundström
Laurence de Leval
Andreas Engert
Dennis A. Eichenauer
Ralf Küppers
Klaus-Dieter Preuss
Martin-Leo Hansmann
Michael Pfreundschuh
author_sort Lorenz Thurner
title Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
title_short Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
title_full Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
title_fullStr Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
title_full_unstemmed Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
title_sort lymphocyte predominant cells detect moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant hodgkin lymphoma
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/99cb03073ee3445083e53f1da680f369
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