CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection

The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and virus susceptibility in the archaeon Sulfolobus...

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Autores principales:	Isabelle Anna Zink, Kevin Pfeifer, Erika Wimmer, Uwe B. Sleytr, Bernhard Schuster, Christa Schleper
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/99d73b21705a4c3e8701c7f8ec1fc53a
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spelling	oai:doaj.org-article:99d73b21705a4c3e8701c7f8ec1fc53a2021-12-02T17:01:32ZCRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection10.1038/s41467-019-12745-x2041-1723https://doaj.org/article/99d73b21705a4c3e8701c7f8ec1fc53a2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12745-xhttps://doaj.org/toc/2041-1723The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and virus susceptibility in the archaeon Sulfolobus solfataricus.Isabelle Anna ZinkKevin PfeiferErika WimmerUwe B. SleytrBernhard SchusterChrista SchleperNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Isabelle Anna Zink Kevin Pfeifer Erika Wimmer Uwe B. Sleytr Bernhard Schuster Christa Schleper CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
description	The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and virus susceptibility in the archaeon Sulfolobus solfataricus.
format	article
author	Isabelle Anna Zink Kevin Pfeifer Erika Wimmer Uwe B. Sleytr Bernhard Schuster Christa Schleper
author_facet	Isabelle Anna Zink Kevin Pfeifer Erika Wimmer Uwe B. Sleytr Bernhard Schuster Christa Schleper
author_sort	Isabelle Anna Zink
title	CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
title_short	CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
title_full	CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
title_fullStr	CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
title_full_unstemmed	CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection
title_sort	crispr-mediated gene silencing reveals involvement of the archaeal s-layer in cell division and virus infection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/99d73b21705a4c3e8701c7f8ec1fc53a
work_keys_str_mv	AT isabelleannazink crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection AT kevinpfeifer crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection AT erikawimmer crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection AT uwebsleytr crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection AT bernhardschuster crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection AT christaschleper crisprmediatedgenesilencingrevealsinvolvementofthearchaealslayerincelldivisionandvirusinfection
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CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection

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