COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES

Objective: To compare intravenous lignocaine vs. intravenous nalbuphine in terms of mean change in heart rate and mean arterial pressures (MAP) during awake tracheal extubation. Study Design: Randomized control trial. Place and Duration of Study: Main Operation Theatre, Combined Military Hospi...

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Autores principales:	Liaquat Ali, Amim Akhter, Muhammad Saeed, Usman Khalid, Jawad Rehmani
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	airway extubation hemodynamics lignocaine mean arterial pressure nalbuphine pulse Medicine R Medicine (General) R5-920
Acceso en línea:	https://doi.org/10.51253/pafmj.v71iSuppl-1.2355 https://doaj.org/article/99e0df7f3eba4a78a54e6e9b57324973
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spelling	oai:doaj.org-article:99e0df7f3eba4a78a54e6e9b573249732021-12-02T17:52:46ZCOMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIEShttps://doi.org/10.51253/pafmj.v71iSuppl-1.23550030-96482411-8842https://doaj.org/article/99e0df7f3eba4a78a54e6e9b573249732021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/2355https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare intravenous lignocaine vs. intravenous nalbuphine in terms of mean change in heart rate and mean arterial pressures (MAP) during awake tracheal extubation. Study Design: Randomized control trial. Place and Duration of Study: Main Operation Theatre, Combined Military Hospital Rawalpindi, from May 2016 to Dec 2016. Methodology: After approval of the study by the institution’s research ethics committee, the patients meeting inclusion criteria were assigned randomly to one of the two groups by lottery method. On return of spontaneous ventilation, patients in group L received intravenous lignocaine 1.5 mg/kg while group N patients received intravenous Nalbuphine 0.2mg/kg. Data recorded immediately (T1) and 5min after (T2) extubation. Results: After stratification of data in terms of age, gender, duration of surgery and ASA classification, evaluation of hemodynamic parameters (HR and MAP) between the two groups was done. The mean change in HR in group L was 6.66 ± 1.53 bpm and in group N was 4.43 ± 1.35. The mean change in MAP in group L was 4.90 ± 1.49 mm of Hg and in group N was 3.23 ± 1.33. p-value in both parameters was found to be less than 0.05 and thus declared significant. Conclusion: We concluded that intravenous nalbuphine, in the dose of 0.2mg/kg, is a better attenuator of hemodynamic response to extubation as compared to intravenous lignocaine and provides better stability of Heart rate and Mean arterial Pressure.Liaquat AliAmim AkhterMuhammad SaeedUsman KhalidJawad RehmaniArmy Medical College Rawalpindiarticleairway extubationhemodynamicslignocainemean arterial pressurenalbuphinepulseMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 37-41 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	airway extubation hemodynamics lignocaine mean arterial pressure nalbuphine pulse Medicine R Medicine (General) R5-920
spellingShingle	airway extubation hemodynamics lignocaine mean arterial pressure nalbuphine pulse Medicine R Medicine (General) R5-920 Liaquat Ali Amim Akhter Muhammad Saeed Usman Khalid Jawad Rehmani COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
description	Objective: To compare intravenous lignocaine vs. intravenous nalbuphine in terms of mean change in heart rate and mean arterial pressures (MAP) during awake tracheal extubation. Study Design: Randomized control trial. Place and Duration of Study: Main Operation Theatre, Combined Military Hospital Rawalpindi, from May 2016 to Dec 2016. Methodology: After approval of the study by the institution’s research ethics committee, the patients meeting inclusion criteria were assigned randomly to one of the two groups by lottery method. On return of spontaneous ventilation, patients in group L received intravenous lignocaine 1.5 mg/kg while group N patients received intravenous Nalbuphine 0.2mg/kg. Data recorded immediately (T1) and 5min after (T2) extubation. Results: After stratification of data in terms of age, gender, duration of surgery and ASA classification, evaluation of hemodynamic parameters (HR and MAP) between the two groups was done. The mean change in HR in group L was 6.66 ± 1.53 bpm and in group N was 4.43 ± 1.35. The mean change in MAP in group L was 4.90 ± 1.49 mm of Hg and in group N was 3.23 ± 1.33. p-value in both parameters was found to be less than 0.05 and thus declared significant. Conclusion: We concluded that intravenous nalbuphine, in the dose of 0.2mg/kg, is a better attenuator of hemodynamic response to extubation as compared to intravenous lignocaine and provides better stability of Heart rate and Mean arterial Pressure.
format	article
author	Liaquat Ali Amim Akhter Muhammad Saeed Usman Khalid Jawad Rehmani
author_facet	Liaquat Ali Amim Akhter Muhammad Saeed Usman Khalid Jawad Rehmani
author_sort	Liaquat Ali
title	COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
title_short	COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
title_full	COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
title_fullStr	COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
title_full_unstemmed	COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES
title_sort	comparison of intravenous lignocaine vs nalbuphine in attenuation of hemodynamic response to awake tracheal extubation in ent surgeries
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doi.org/10.51253/pafmj.v71iSuppl-1.2355 https://doaj.org/article/99e0df7f3eba4a78a54e6e9b57324973
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COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES

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