Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study

Abstract The purpose of the present study was to compare the relative absorption of a new powder presentation of silicon (Si) as orthosilicic acid with maltodextrin (Orgono Powder) compared to usual Si liquid presentations as orthosilicic acid with Equisetum arvense and Rosmarinus officinalis (G5 Si...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	N. Boqué, R. M. Valls, A. Pedret, F. Puiggrós, L. Arola, R. Solà
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/99e1d52637e04fe48ce6e23fdf9422f3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:99e1d52637e04fe48ce6e23fdf9422f3
record_format	dspace
spelling	oai:doaj.org-article:99e1d52637e04fe48ce6e23fdf9422f32021-12-02T15:08:22ZRelative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study10.1038/s41598-021-95220-22045-2322https://doaj.org/article/99e1d52637e04fe48ce6e23fdf9422f32021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95220-2https://doaj.org/toc/2045-2322Abstract The purpose of the present study was to compare the relative absorption of a new powder presentation of silicon (Si) as orthosilicic acid with maltodextrin (Orgono Powder) compared to usual Si liquid presentations as orthosilicic acid with Equisetum arvense and Rosmarinus officinalis (G5 Siliplant) and orthosilicic acid with aloe vera (G7 Aloe). All dietary supplements were administered at the same Si oral dose (21.6 mg) in a randomized, double-blind, crossover post-prandial study conducted in 5 healthy men. Urine was collected at baseline and over the 6-h post-dose period in 2 separate 3-h collections for the analysis of Si concentration, which was conducted by inductively coupled plasma optical emission spectrometry as the gold standard method. No significant differences in total urinary Si excretion were found after the intake of these 3 dietary supplements; 34.6%, 32.4% and 27.2% of the ingested Si from G7 Aloe, G5 Siliplant and Orgono Powder, respectively, was excreted in urine over the 6-h follow-up period. The 3 different oral Si formulations tested, in powder and liquid presentations, provide highly bioavailable Si and present an equivalent relative absorption in healthy humans.N. BoquéR. M. VallsA. PedretF. PuiggrósL. ArolaR. SolàNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q N. Boqué R. M. Valls A. Pedret F. Puiggrós L. Arola R. Solà Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
description	Abstract The purpose of the present study was to compare the relative absorption of a new powder presentation of silicon (Si) as orthosilicic acid with maltodextrin (Orgono Powder) compared to usual Si liquid presentations as orthosilicic acid with Equisetum arvense and Rosmarinus officinalis (G5 Siliplant) and orthosilicic acid with aloe vera (G7 Aloe). All dietary supplements were administered at the same Si oral dose (21.6 mg) in a randomized, double-blind, crossover post-prandial study conducted in 5 healthy men. Urine was collected at baseline and over the 6-h post-dose period in 2 separate 3-h collections for the analysis of Si concentration, which was conducted by inductively coupled plasma optical emission spectrometry as the gold standard method. No significant differences in total urinary Si excretion were found after the intake of these 3 dietary supplements; 34.6%, 32.4% and 27.2% of the ingested Si from G7 Aloe, G5 Siliplant and Orgono Powder, respectively, was excreted in urine over the 6-h follow-up period. The 3 different oral Si formulations tested, in powder and liquid presentations, provide highly bioavailable Si and present an equivalent relative absorption in healthy humans.
format	article
author	N. Boqué R. M. Valls A. Pedret F. Puiggrós L. Arola R. Solà
author_facet	N. Boqué R. M. Valls A. Pedret F. Puiggrós L. Arola R. Solà
author_sort	N. Boqué
title	Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
title_short	Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
title_full	Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
title_fullStr	Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
title_full_unstemmed	Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
title_sort	relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/99e1d52637e04fe48ce6e23fdf9422f3
work_keys_str_mv	AT nboque relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy AT rmvalls relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy AT apedret relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy AT fpuiggros relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy AT larola relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy AT rsola relativeabsorptionofsiliconfromdifferentformulationsofdietarysupplementsapilotrandomizeddoubleblindcrossoverpostprandialstudy
_version_	1718388202434199552

Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study

Ejemplares similares