Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli

Multi-omics data integration is a great challenge. Here, the authors compile a database of E. coliproteomics, transcriptomics, metabolomics and fluxomics data to train models of recurrent neural network and constrained regression, enabling prediction of bacterial responses to perturbations.

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Bibliographic Details
Main Authors: Minseung Kim, Navneet Rai, Violeta Zorraquino, Ilias Tagkopoulos
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
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Online Access:https://doaj.org/article/99ed3ae0d5e148ff8d397f4572e0ceba
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