Hepatocellular Carcinoma Cells Are Protected From Immunolysis by Mesenchymal Stromal Cells Through Indoleamine 2,3 Dioxygenase
B7 family proteins serve as checkpoint molecules that protect tumors from T cell mediated lysis. Tryptophan degrading enzymes indoleamine 2,3 dioxygenase (IDO) and tryptophan 2,3 dioxygenase (TDO) also induce T cell immune tolerance. However, little is known about the relative contribution of B7 mol...
Guardado en:
Autores principales: | Raghavan Chinnadurai, Amanda Paige Porter, Mihir Patel, Ariel Joy Lipat, Mathews H. Forsberg, Devi Rajan, Peiman Hematti, Christian M. Capitini, Charles Bruker |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/99ee81a0e482403ab182d77d66ad8b4a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
TRYPTOPHAN AND INDOLEAMINE-2,3-DIOXYGENASE (IDO) IN PATHOGENESIS OF IMMUNOSUPPRESSIVE CLINICAL CONDITIONS
por: V. A. Kozlov, et al.
Publicado: (2017) -
Indoleamine-2,3-Dioxygenase as a Perioperative Marker of the Immune System
por: Corina Bello, et al.
Publicado: (2021) -
The Function of the Kynurenine Pathway in the Placenta: A Novel Pharmacotherapeutic Target?
por: Michelle Broekhuizen, et al.
Publicado: (2021) -
Short- and Long-Term Immunological Responses in Chronic HCV/HIV Co-Infected Compared to HCV Mono-Infected Patients after DAA Therapy
por: Stefania Farcomeni, et al.
Publicado: (2021) -
Emerging Roles on Immunological Effect of Indoleamine 2,3-Dioxygenase in Liver Injuries
por: Lingyan Xu, et al.
Publicado: (2021)