Optoregulated force application to cellular receptors using molecular motors

Molecular scale force application in physiological environments is important for studying mechanotransduction. Here, the authors use a molecular machine to apply forces at cell-matrix and cell-cell junctions using light to trigger twisting actuation which then pulls on cell membrane receptors.

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Detalles Bibliográficos
Autores principales:	Yijun Zheng, Mitchell K. L. Han, Renping Zhao, Johanna Blass, Jingnan Zhang, Dennis W. Zhou, Jean-Rémy Colard-Itté, Damien Dattler, Arzu Çolak, Markus Hoth, Andrés J. García, Bin Qu, Roland Bennewitz, Nicolas Giuseppone, Aránzazu del Campo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/99ef1624e3384f9da8cdb45685e4e0bb
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spelling	oai:doaj.org-article:99ef1624e3384f9da8cdb45685e4e0bb2021-12-02T17:34:47ZOptoregulated force application to cellular receptors using molecular motors10.1038/s41467-021-23815-42041-1723https://doaj.org/article/99ef1624e3384f9da8cdb45685e4e0bb2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23815-4https://doaj.org/toc/2041-1723Molecular scale force application in physiological environments is important for studying mechanotransduction. Here, the authors use a molecular machine to apply forces at cell-matrix and cell-cell junctions using light to trigger twisting actuation which then pulls on cell membrane receptors.Yijun ZhengMitchell K. L. HanRenping ZhaoJohanna BlassJingnan ZhangDennis W. ZhouJean-Rémy Colard-IttéDamien DattlerArzu ÇolakMarkus HothAndrés J. GarcíaBin QuRoland BennewitzNicolas GiusepponeAránzazu del CampoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yijun Zheng Mitchell K. L. Han Renping Zhao Johanna Blass Jingnan Zhang Dennis W. Zhou Jean-Rémy Colard-Itté Damien Dattler Arzu Çolak Markus Hoth Andrés J. García Bin Qu Roland Bennewitz Nicolas Giuseppone Aránzazu del Campo Optoregulated force application to cellular receptors using molecular motors
description	Molecular scale force application in physiological environments is important for studying mechanotransduction. Here, the authors use a molecular machine to apply forces at cell-matrix and cell-cell junctions using light to trigger twisting actuation which then pulls on cell membrane receptors.
format	article
author	Yijun Zheng Mitchell K. L. Han Renping Zhao Johanna Blass Jingnan Zhang Dennis W. Zhou Jean-Rémy Colard-Itté Damien Dattler Arzu Çolak Markus Hoth Andrés J. García Bin Qu Roland Bennewitz Nicolas Giuseppone Aránzazu del Campo
author_facet	Yijun Zheng Mitchell K. L. Han Renping Zhao Johanna Blass Jingnan Zhang Dennis W. Zhou Jean-Rémy Colard-Itté Damien Dattler Arzu Çolak Markus Hoth Andrés J. García Bin Qu Roland Bennewitz Nicolas Giuseppone Aránzazu del Campo
author_sort	Yijun Zheng
title	Optoregulated force application to cellular receptors using molecular motors
title_short	Optoregulated force application to cellular receptors using molecular motors
title_full	Optoregulated force application to cellular receptors using molecular motors
title_fullStr	Optoregulated force application to cellular receptors using molecular motors
title_full_unstemmed	Optoregulated force application to cellular receptors using molecular motors
title_sort	optoregulated force application to cellular receptors using molecular motors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/99ef1624e3384f9da8cdb45685e4e0bb
work_keys_str_mv	AT yijunzheng optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT mitchellklhan optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT renpingzhao optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT johannablass optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT jingnanzhang optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT denniswzhou optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT jeanremycolarditte optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT damiendattler optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT arzucolak optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT markushoth optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT andresjgarcia optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT binqu optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT rolandbennewitz optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT nicolasgiuseppone optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors AT aranzazudelcampo optoregulatedforceapplicationtocellularreceptorsusingmolecularmotors
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Optoregulated force application to cellular receptors using molecular motors

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