ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion

The acid-sensing ion channel, ASIC1a, is known to play a role in synaptic transmission and plasticity. Here, the authors demonstrate a role for ASIC1a in regulating plasticity in the insular cortex and find that extinction of conditioned taste aversion memory is disrupted in the ASIC1a knockout mice...

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Autores principales:	Wei-Guang Li, Ming-Gang Liu, Shining Deng, Yan-Mei Liu, Lin Shang, Jing Ding, Tsan-Ting Hsu, Qin Jiang, Ying Li, Fei Li, Michael Xi Zhu, Tian-Le Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/99fe6ce426ce4f2787c770e0871005d1
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spelling	oai:doaj.org-article:99fe6ce426ce4f2787c770e0871005d12021-12-02T14:39:50ZASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion10.1038/ncomms137702041-1723https://doaj.org/article/99fe6ce426ce4f2787c770e0871005d12016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13770https://doaj.org/toc/2041-1723The acid-sensing ion channel, ASIC1a, is known to play a role in synaptic transmission and plasticity. Here, the authors demonstrate a role for ASIC1a in regulating plasticity in the insular cortex and find that extinction of conditioned taste aversion memory is disrupted in the ASIC1a knockout mice.Wei-Guang LiMing-Gang LiuShining DengYan-Mei LiuLin ShangJing DingTsan-Ting HsuQin JiangYing LiFei LiMichael Xi ZhuTian-Le XuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei-Guang Li Ming-Gang Liu Shining Deng Yan-Mei Liu Lin Shang Jing Ding Tsan-Ting Hsu Qin Jiang Ying Li Fei Li Michael Xi Zhu Tian-Le Xu ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
description	The acid-sensing ion channel, ASIC1a, is known to play a role in synaptic transmission and plasticity. Here, the authors demonstrate a role for ASIC1a in regulating plasticity in the insular cortex and find that extinction of conditioned taste aversion memory is disrupted in the ASIC1a knockout mice.
format	article
author	Wei-Guang Li Ming-Gang Liu Shining Deng Yan-Mei Liu Lin Shang Jing Ding Tsan-Ting Hsu Qin Jiang Ying Li Fei Li Michael Xi Zhu Tian-Le Xu
author_facet	Wei-Guang Li Ming-Gang Liu Shining Deng Yan-Mei Liu Lin Shang Jing Ding Tsan-Ting Hsu Qin Jiang Ying Li Fei Li Michael Xi Zhu Tian-Le Xu
author_sort	Wei-Guang Li
title	ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
title_short	ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
title_full	ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
title_fullStr	ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
title_full_unstemmed	ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
title_sort	asic1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/99fe6ce426ce4f2787c770e0871005d1
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ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion

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