The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique
Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:99ff6b5e2fd74cacaefd75c3009d69362021-12-01T13:09:45ZThe First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique2296-256510.3389/fpubh.2021.764201https://doaj.org/article/99ff6b5e2fd74cacaefd75c3009d69362021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpubh.2021.764201/fullhttps://doaj.org/toc/2296-2565Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed where one of the major epidemiological studies on indoor radon demonstrated an increased risk of lung cancer. We analyzed data from a hospital-based case-control study that included 30 lung cancer cases and 39 controls with special attention to internal exposure assessment based on the discriminative measurement technique of radon isotopes. Results from the analyses showed non-significant increased lung cancer risks; odds ratios (ORs) adjusted for age, smoking, and total income were 0.35 (95% CI: 0.07–1.74) and 0.27 (95% CI: 0.04–1.74) for groups living in residences with indoor radon concentrations of 50–100 Bq m−3 and over 100 Bq m−3, respectively, compared with those with < 50 Bq m−3 indoor radon concentrations. Although the small sample size hampers the usefulness of present analyses, our study suggests that reevaluation of lung cancer risk associated with residential radon in the epidemiological studies will be required on the basis of precise exposure assessment.Hiromi KudoShinji YoshinagaShinji YoshinagaXiaoliang LiShujie LeiShouzhi ZhangQuanfu SunChihaya KoriyamaSuminori AkibaShinji TokonamiFrontiers Media S.A.articleresidentialradonthoronlung cancercase-control studyPublic aspects of medicineRA1-1270ENFrontiers in Public Health, Vol 9 (2021) |
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residential radon thoron lung cancer case-control study Public aspects of medicine RA1-1270 |
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residential radon thoron lung cancer case-control study Public aspects of medicine RA1-1270 Hiromi Kudo Shinji Yoshinaga Shinji Yoshinaga Xiaoliang Li Shujie Lei Shouzhi Zhang Quanfu Sun Chihaya Koriyama Suminori Akiba Shinji Tokonami The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| description |
Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed where one of the major epidemiological studies on indoor radon demonstrated an increased risk of lung cancer. We analyzed data from a hospital-based case-control study that included 30 lung cancer cases and 39 controls with special attention to internal exposure assessment based on the discriminative measurement technique of radon isotopes. Results from the analyses showed non-significant increased lung cancer risks; odds ratios (ORs) adjusted for age, smoking, and total income were 0.35 (95% CI: 0.07–1.74) and 0.27 (95% CI: 0.04–1.74) for groups living in residences with indoor radon concentrations of 50–100 Bq m−3 and over 100 Bq m−3, respectively, compared with those with < 50 Bq m−3 indoor radon concentrations. Although the small sample size hampers the usefulness of present analyses, our study suggests that reevaluation of lung cancer risk associated with residential radon in the epidemiological studies will be required on the basis of precise exposure assessment. |
| format |
article |
| author |
Hiromi Kudo Shinji Yoshinaga Shinji Yoshinaga Xiaoliang Li Shujie Lei Shouzhi Zhang Quanfu Sun Chihaya Koriyama Suminori Akiba Shinji Tokonami |
| author_facet |
Hiromi Kudo Shinji Yoshinaga Shinji Yoshinaga Xiaoliang Li Shujie Lei Shouzhi Zhang Quanfu Sun Chihaya Koriyama Suminori Akiba Shinji Tokonami |
| author_sort |
Hiromi Kudo |
| title |
The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| title_short |
The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| title_full |
The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| title_fullStr |
The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| title_full_unstemmed |
The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
| title_sort |
first attempt to reevaluate radon and thoron exposure in gansu province study using radon-thoron discriminating measurement technique |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/99ff6b5e2fd74cacaefd75c3009d6936 |
| work_keys_str_mv |
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