Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty

Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty

Bryan S Lee,1,2 David R Hardten21Department of Ophthalmology, University of Washington, Seattle, WA, 2Minnesota Eye Consultants, Minneapolis, MN, USABackground: Patients with endothelial disease also often have scarring or surface corneal disease. This study examined the outcomes of phototherapeuti...

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Autores principales: Lee BS, Hardten DR
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2014
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/9a0f992e96b3415d83771ef1998b8bc3
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spelling oai:doaj.org-article:9a0f992e96b3415d83771ef1998b8bc32021-12-02T04:45:46ZVisual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty1177-5483https://doaj.org/article/9a0f992e96b3415d83771ef1998b8bc32014-05-01T00:00:00Zhttp://www.dovepress.com/visual-and-subjective-outcomes-of-phototherapeutic-keratectomy-after-d-a16906https://doaj.org/toc/1177-5483 Bryan S Lee,1,2 David R Hardten21Department of Ophthalmology, University of Washington, Seattle, WA, 2Minnesota Eye Consultants, Minneapolis, MN, USABackground: Patients with endothelial disease also often have scarring or surface corneal disease. This study examined the outcomes of phototherapeutic keratectomy (PTK) performed in patients with prior Descemet’s stripping endothelial keratoplasty (DSEK).Methods: This retrospective case series examined all patients undergoing PTK after DSEK in a single private practice. The primary outcome was best-corrected visual acuity, with secondary outcomes of change in spherical equivalent versus targeted change, change in endothelial cell count, improvement in corneal topography, and subjective satisfaction with vision.Results: For the ten patients who met the inclusion criteria, mean best-corrected visual acuity improved from logarithm of the minimum angle of resolution (logMAR) 0.43 to 0.36 (P=0.24) at the most recent postoperative visit. PTK treatments that included a refractive component showed good predictability of 1.13 diopters spherical equivalent/diopter attempted. There was no evidence of a decrease in endothelial cell count from PTK, even with the use of mitomycin C (P=0.95). Subjectively, 80% of patients noted improvement in their vision. Conclusion: PTK after DSEK has the potential to improve patients’ vision with high levels of patient satisfaction, even though many patients had significant ocular comorbidities. Surgeons should consider using PTK to treat anterior corneal pathology following DSEK.Keywords: phototherapeutic keratectomy, Descemet’s stripping endothelial keratoplasty, anterior basement membrane dystrophy, irregular astigmatismLee BSHardten DRDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 1011-1015 (2014)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Lee BS
Hardten DR
Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
description Bryan S Lee,1,2 David R Hardten21Department of Ophthalmology, University of Washington, Seattle, WA, 2Minnesota Eye Consultants, Minneapolis, MN, USABackground: Patients with endothelial disease also often have scarring or surface corneal disease. This study examined the outcomes of phototherapeutic keratectomy (PTK) performed in patients with prior Descemet’s stripping endothelial keratoplasty (DSEK).Methods: This retrospective case series examined all patients undergoing PTK after DSEK in a single private practice. The primary outcome was best-corrected visual acuity, with secondary outcomes of change in spherical equivalent versus targeted change, change in endothelial cell count, improvement in corneal topography, and subjective satisfaction with vision.Results: For the ten patients who met the inclusion criteria, mean best-corrected visual acuity improved from logarithm of the minimum angle of resolution (logMAR) 0.43 to 0.36 (P=0.24) at the most recent postoperative visit. PTK treatments that included a refractive component showed good predictability of 1.13 diopters spherical equivalent/diopter attempted. There was no evidence of a decrease in endothelial cell count from PTK, even with the use of mitomycin C (P=0.95). Subjectively, 80% of patients noted improvement in their vision. Conclusion: PTK after DSEK has the potential to improve patients’ vision with high levels of patient satisfaction, even though many patients had significant ocular comorbidities. Surgeons should consider using PTK to treat anterior corneal pathology following DSEK.Keywords: phototherapeutic keratectomy, Descemet’s stripping endothelial keratoplasty, anterior basement membrane dystrophy, irregular astigmatism
format article
author Lee BS
Hardten DR
author_facet Lee BS
Hardten DR
author_sort Lee BS
title Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
title_short Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
title_full Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
title_fullStr Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
title_full_unstemmed Visual and subjective outcomes of phototherapeutic keratectomy after Descemet’s stripping endothelial keratoplasty
title_sort visual and subjective outcomes of phototherapeutic keratectomy after descemet’s stripping endothelial keratoplasty
publisher Dove Medical Press
publishDate 2014
url https://doaj.org/article/9a0f992e96b3415d83771ef1998b8bc3
work_keys_str_mv AT leebs visualandsubjectiveoutcomesofphototherapeutickeratectomyafterdescemetrsquosstrippingendothelialkeratoplasty
AT hardtendr visualandsubjectiveoutcomesofphototherapeutickeratectomyafterdescemetrsquosstrippingendothelialkeratoplasty
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