A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation

Allograft can induces local chronic inflammation, but how this feeds back to regulating late immunity is still not clear. Here the authors show, by charactering B cell transcriptome landscape dynamic in human allografts and in mouse kidneys transitioning from acute to chronic injury, that late B cel...

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Autores principales:	Pietro E. Cippà, Jing Liu, Bo Sun, Sanjeev Kumar, Maarten Naesens, Andrew P. McMahon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9a1302d9fdc74657b9d80933900e5492
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spelling	oai:doaj.org-article:9a1302d9fdc74657b9d80933900e54922021-12-02T16:57:12ZA late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation10.1038/s41467-019-09092-22041-1723https://doaj.org/article/9a1302d9fdc74657b9d80933900e54922019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09092-2https://doaj.org/toc/2041-1723Allograft can induces local chronic inflammation, but how this feeds back to regulating late immunity is still not clear. Here the authors show, by charactering B cell transcriptome landscape dynamic in human allografts and in mouse kidneys transitioning from acute to chronic injury, that late B cell activation is associated with renal dysfunction and inflammation.Pietro E. CippàJing LiuBo SunSanjeev KumarMaarten NaesensAndrew P. McMahonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pietro E. Cippà Jing Liu Bo Sun Sanjeev Kumar Maarten Naesens Andrew P. McMahon A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
description	Allograft can induces local chronic inflammation, but how this feeds back to regulating late immunity is still not clear. Here the authors show, by charactering B cell transcriptome landscape dynamic in human allografts and in mouse kidneys transitioning from acute to chronic injury, that late B cell activation is associated with renal dysfunction and inflammation.
format	article
author	Pietro E. Cippà Jing Liu Bo Sun Sanjeev Kumar Maarten Naesens Andrew P. McMahon
author_facet	Pietro E. Cippà Jing Liu Bo Sun Sanjeev Kumar Maarten Naesens Andrew P. McMahon
author_sort	Pietro E. Cippà
title	A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
title_short	A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
title_full	A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
title_fullStr	A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
title_full_unstemmed	A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
title_sort	late b lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9a1302d9fdc74657b9d80933900e5492
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A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation

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