Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and <named-content content-type="genus-species">Staphylococcus aureus</named-content> Sepsis in Mice

ABSTRACT Staphylococcal enterotoxin B (SEB) is a potent toxin that is produced by Staphylococcus aureus strains and is classified as a category B select agent. We have previously shown that monoclonal antibody (MAb) 20B1, a murine anti-SEB IgG1, successfully treats SEB-induced lethal shock (SEBILS)...

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Autores principales: Avanish K. Varshney, Xiaobo Wang, Jorge L. Aguilar, Matthew D. Scharff, Bettina C. Fries
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/9a1c1236fdbd4c7db1e1affd15b352e6
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