Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases

Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures associated with distinct disease states.

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Detalles Bibliográficos
Autores principales: Samuel J. S. Rubin, Lawrence Bai, Yeneneh Haileselassie, Gotzone Garay, Chohee Yun, Laren Becker, Sarah E. Streett, Sidhartha R. Sinha, Aida Habtezion
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9a229a7519d7425b9121ac0a514fa771
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Sumario:Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures associated with distinct disease states.