Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases

Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures associated with distinct disease states.

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Autores principales: Samuel J. S. Rubin, Lawrence Bai, Yeneneh Haileselassie, Gotzone Garay, Chohee Yun, Laren Becker, Sarah E. Streett, Sidhartha R. Sinha, Aida Habtezion
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9a229a7519d7425b9121ac0a514fa771
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spelling oai:doaj.org-article:9a229a7519d7425b9121ac0a514fa7712021-12-02T17:02:11ZMass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases10.1038/s41467-019-10387-72041-1723https://doaj.org/article/9a229a7519d7425b9121ac0a514fa7712019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10387-7https://doaj.org/toc/2041-1723Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures associated with distinct disease states.Samuel J. S. RubinLawrence BaiYeneneh HaileselassieGotzone GarayChohee YunLaren BeckerSarah E. StreettSidhartha R. SinhaAida HabtezionNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Samuel J. S. Rubin
Lawrence Bai
Yeneneh Haileselassie
Gotzone Garay
Chohee Yun
Laren Becker
Sarah E. Streett
Sidhartha R. Sinha
Aida Habtezion
Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
description Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures associated with distinct disease states.
format article
author Samuel J. S. Rubin
Lawrence Bai
Yeneneh Haileselassie
Gotzone Garay
Chohee Yun
Laren Becker
Sarah E. Streett
Sidhartha R. Sinha
Aida Habtezion
author_facet Samuel J. S. Rubin
Lawrence Bai
Yeneneh Haileselassie
Gotzone Garay
Chohee Yun
Laren Becker
Sarah E. Streett
Sidhartha R. Sinha
Aida Habtezion
author_sort Samuel J. S. Rubin
title Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
title_short Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
title_full Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
title_fullStr Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
title_full_unstemmed Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
title_sort mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9a229a7519d7425b9121ac0a514fa771
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