Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss

Abstract Synucleinopathies are neurodegenerative diseases in which α-synuclein protein accumulates in neurons and glia. In these diseases, α-synuclein forms dense intracellular aggregates that are disease hallmarks and actively contribute to tissue pathology. Interestingly, many pathological mechani...

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Bibliographic Details
Main Authors: Andrew D. Sauerbeck, Evan Z. Goldstein, Anthony N. Alfredo, Michael Norenberg, Alexander Marcillo, Dana M. McTigue
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/9a2dff3f6e0e49ada4d12e2e9197b909
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