Virus-derived DNA drives mosquito vector tolerance to arboviral infection

Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of viral-derived DNA by cellular reverse transcriptas...

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Autores principales: Bertsy Goic, Kenneth A. Stapleford, Lionel Frangeul, Aurélien J. Doucet, Valérie Gausson, Hervé Blanc, Nidia Schemmel-Jofre, Gael Cristofari, Louis Lambrechts, Marco Vignuzzi, Maria-Carla Saleh
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/9a39bc0ccc7846528320a2473d103edd
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spelling oai:doaj.org-article:9a39bc0ccc7846528320a2473d103edd2021-12-02T16:57:18ZVirus-derived DNA drives mosquito vector tolerance to arboviral infection10.1038/ncomms124102041-1723https://doaj.org/article/9a39bc0ccc7846528320a2473d103edd2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12410https://doaj.org/toc/2041-1723Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of viral-derived DNA by cellular reverse transcriptases.Bertsy GoicKenneth A. StaplefordLionel FrangeulAurélien J. DoucetValérie GaussonHervé BlancNidia Schemmel-JofreGael CristofariLouis LambrechtsMarco VignuzziMaria-Carla SalehNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bertsy Goic
Kenneth A. Stapleford
Lionel Frangeul
Aurélien J. Doucet
Valérie Gausson
Hervé Blanc
Nidia Schemmel-Jofre
Gael Cristofari
Louis Lambrechts
Marco Vignuzzi
Maria-Carla Saleh
Virus-derived DNA drives mosquito vector tolerance to arboviral infection
description Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of viral-derived DNA by cellular reverse transcriptases.
format article
author Bertsy Goic
Kenneth A. Stapleford
Lionel Frangeul
Aurélien J. Doucet
Valérie Gausson
Hervé Blanc
Nidia Schemmel-Jofre
Gael Cristofari
Louis Lambrechts
Marco Vignuzzi
Maria-Carla Saleh
author_facet Bertsy Goic
Kenneth A. Stapleford
Lionel Frangeul
Aurélien J. Doucet
Valérie Gausson
Hervé Blanc
Nidia Schemmel-Jofre
Gael Cristofari
Louis Lambrechts
Marco Vignuzzi
Maria-Carla Saleh
author_sort Bertsy Goic
title Virus-derived DNA drives mosquito vector tolerance to arboviral infection
title_short Virus-derived DNA drives mosquito vector tolerance to arboviral infection
title_full Virus-derived DNA drives mosquito vector tolerance to arboviral infection
title_fullStr Virus-derived DNA drives mosquito vector tolerance to arboviral infection
title_full_unstemmed Virus-derived DNA drives mosquito vector tolerance to arboviral infection
title_sort virus-derived dna drives mosquito vector tolerance to arboviral infection
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/9a39bc0ccc7846528320a2473d103edd
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