Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children

Objective: To determine the factors associated with severe ALRTI from RSV in children. Materials and Methods: A retrospective study of children aged 1-60 months were conducted from 2014 to 2018. Out of 269 patients diagnosed with RSV ALRTI, 100 children were enrolled in the study, 20 had severe RSV...

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Autores principales:	Atipotsawee Tungsupreechameth, Klaita Srisingh
Formato:	article
Lenguaje:	EN
Publicado:	Mahidol University 2021
Materias:	Lower respiratory tract infections respiratory syncytial virus risk factor Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9a3d0c58d8e24728817408b877f4cf5f
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spelling	oai:doaj.org-article:9a3d0c58d8e24728817408b877f4cf5f2021-12-01T10:07:39ZFactors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children10.33192/Smj.2021.1052228-8082https://doaj.org/article/9a3d0c58d8e24728817408b877f4cf5f2021-12-01T00:00:00Zhttps://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/254581https://doaj.org/toc/2228-8082 Objective: To determine the factors associated with severe ALRTI from RSV in children. Materials and Methods: A retrospective study of children aged 1-60 months were conducted from 2014 to 2018. Out of 269 patients diagnosed with RSV ALRTI, 100 children were enrolled in the study, 20 had severe RSV ALRTI, while 80 had non-severe RSV ALRTI as identified by the ReSVinet scale. A multivariable logistic model was conducted to select significant variables. Results: During the study period, 269 patients were diagnosed with RSV ALRTI. Mean age was 10.45 ± 3.53 months. Clinical manifestations of severe RSV ALRTI group had significant difference in abnormal general condition (P < 0.001), tachypnea (P < 0.001), SpO2 < 85% (P < 0.001), poor air entry in lungs (P < 0.001), and retraction (P < 0.001). The factors associated with severe RSV ALRTI group, were underlying congenital heart disease [aOR 32.45; 95% CI 3.38-311.87, P = 0.003] and duration of hospital stay >5 days [aOR 19.56; 95% CI 1.81-212.05, P = 0.014]. Conclusion: Factors associated with severe RSV ALRTI in children were underlying congenital heart disease and duration of hospital stay >5 days. Atipotsawee TungsupreechamethKlaita SrisinghMahidol UniversityarticleLower respiratory tract infectionsrespiratory syncytial virusrisk factorMedicine (General)R5-920ENSiriraj Medical Journal, Vol 73, Iss 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Lower respiratory tract infections respiratory syncytial virus risk factor Medicine (General) R5-920
spellingShingle	Lower respiratory tract infections respiratory syncytial virus risk factor Medicine (General) R5-920 Atipotsawee Tungsupreechameth Klaita Srisingh Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
description	Objective: To determine the factors associated with severe ALRTI from RSV in children. Materials and Methods: A retrospective study of children aged 1-60 months were conducted from 2014 to 2018. Out of 269 patients diagnosed with RSV ALRTI, 100 children were enrolled in the study, 20 had severe RSV ALRTI, while 80 had non-severe RSV ALRTI as identified by the ReSVinet scale. A multivariable logistic model was conducted to select significant variables. Results: During the study period, 269 patients were diagnosed with RSV ALRTI. Mean age was 10.45 ± 3.53 months. Clinical manifestations of severe RSV ALRTI group had significant difference in abnormal general condition (P < 0.001), tachypnea (P < 0.001), SpO2 < 85% (P < 0.001), poor air entry in lungs (P < 0.001), and retraction (P < 0.001). The factors associated with severe RSV ALRTI group, were underlying congenital heart disease [aOR 32.45; 95% CI 3.38-311.87, P = 0.003] and duration of hospital stay >5 days [aOR 19.56; 95% CI 1.81-212.05, P = 0.014]. Conclusion: Factors associated with severe RSV ALRTI in children were underlying congenital heart disease and duration of hospital stay >5 days.
format	article
author	Atipotsawee Tungsupreechameth Klaita Srisingh
author_facet	Atipotsawee Tungsupreechameth Klaita Srisingh
author_sort	Atipotsawee Tungsupreechameth
title	Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
title_short	Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
title_full	Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
title_fullStr	Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
title_full_unstemmed	Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children
title_sort	factors associated with severe lower respiratory tract infection from respiratory syncytial virus (rsv) in thai children
publisher	Mahidol University
publishDate	2021
url	https://doaj.org/article/9a3d0c58d8e24728817408b877f4cf5f
work_keys_str_mv	AT atipotsaweetungsupreechameth factorsassociatedwithseverelowerrespiratorytractinfectionfromrespiratorysyncytialvirusrsvinthaichildren AT klaitasrisingh factorsassociatedwithseverelowerrespiratorytractinfectionfromrespiratorysyncytialvirusrsvinthaichildren
_version_	1718405312501776384

Factors Associated with Severe Lower Respiratory Tract Infection from Respiratory Syncytial Virus (RSV) in Thai Children

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