Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find signals of genetic associations with stomach region.

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Autores principales:	Florent Ailloud, Xavier Didelot, Sabrina Woltemate, Gudrun Pfaffinger, Jörg Overmann, Ruth Christiane Bader, Christian Schulz, Peter Malfertheiner, Sebastian Suerbaum
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9a3e48a0d62246e483c72c41e2e85902
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spelling	oai:doaj.org-article:9a3e48a0d62246e483c72c41e2e859022021-12-02T16:58:24ZWithin-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps10.1038/s41467-019-10050-12041-1723https://doaj.org/article/9a3e48a0d62246e483c72c41e2e859022019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10050-1https://doaj.org/toc/2041-1723Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find signals of genetic associations with stomach region.Florent AilloudXavier DidelotSabrina WoltemateGudrun PfaffingerJörg OvermannRuth Christiane BaderChristian SchulzPeter MalfertheinerSebastian SuerbaumNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Florent Ailloud Xavier Didelot Sabrina Woltemate Gudrun Pfaffinger Jörg Overmann Ruth Christiane Bader Christian Schulz Peter Malfertheiner Sebastian Suerbaum Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
description	Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find signals of genetic associations with stomach region.
format	article
author	Florent Ailloud Xavier Didelot Sabrina Woltemate Gudrun Pfaffinger Jörg Overmann Ruth Christiane Bader Christian Schulz Peter Malfertheiner Sebastian Suerbaum
author_facet	Florent Ailloud Xavier Didelot Sabrina Woltemate Gudrun Pfaffinger Jörg Overmann Ruth Christiane Bader Christian Schulz Peter Malfertheiner Sebastian Suerbaum
author_sort	Florent Ailloud
title	Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
title_short	Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
title_full	Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
title_fullStr	Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
title_full_unstemmed	Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
title_sort	within-host evolution of helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9a3e48a0d62246e483c72c41e2e85902
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Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

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