Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find signals of genetic associations with stomach region.

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Autores principales: Florent Ailloud, Xavier Didelot, Sabrina Woltemate, Gudrun Pfaffinger, Jörg Overmann, Ruth Christiane Bader, Christian Schulz, Peter Malfertheiner, Sebastian Suerbaum
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9a3e48a0d62246e483c72c41e2e85902
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