Topical Medication Therapy for Glaucoma and Ocular Hypertension

Glaucoma is one of the most common causes of blindness, thus seriously affecting people’s health and quality of life. The topical medical therapy is as the first line treatment in the management of glaucoma since it is inexpensive, convenient, effective, and safe. This review summarizes and compares...

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Autores principales:	Tao Wang, Linlin Cao, Qikun Jiang, Tianhong Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	glaucoma monotherapy fixed combination therapy non-fixed combination therapy intraocular pressure adverse effects Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/9a431718bd274d4cab37383978bd6879
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id	oai:doaj.org-article:9a431718bd274d4cab37383978bd6879
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spelling	oai:doaj.org-article:9a431718bd274d4cab37383978bd68792021-12-02T00:04:32ZTopical Medication Therapy for Glaucoma and Ocular Hypertension1663-981210.3389/fphar.2021.749858https://doaj.org/article/9a431718bd274d4cab37383978bd68792021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphar.2021.749858/fullhttps://doaj.org/toc/1663-9812Glaucoma is one of the most common causes of blindness, thus seriously affecting people’s health and quality of life. The topical medical therapy is as the first line treatment in the management of glaucoma since it is inexpensive, convenient, effective, and safe. This review summarizes and compares extensive clinical trials on the topical medications for the treatment of glaucoma, including topical monotherapy agents, topical fixed-combination agents, topical non-fixed combination agents, and their composition, mechanism of action, efficacy, and adverse effects, which will provide reference for optimal choice of clinical medication. Fixed-combination therapeutics offer greater efficacy, reliable security, clinical compliance, and tolerance than non-fixed combination agents and monotherapy agents, which will become a prefer option for the treatment of glaucoma. Meanwhile, we also discuss new trends in the field of new fixed combinations of medications, which may better control IOP and treat glaucoma.Tao WangLinlin CaoQikun JiangTianhong ZhangFrontiers Media S.A.articleglaucomamonotherapyfixed combination therapynon-fixed combination therapyintraocular pressureadverse effectsTherapeutics. PharmacologyRM1-950ENFrontiers in Pharmacology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	glaucoma monotherapy fixed combination therapy non-fixed combination therapy intraocular pressure adverse effects Therapeutics. Pharmacology RM1-950
spellingShingle	glaucoma monotherapy fixed combination therapy non-fixed combination therapy intraocular pressure adverse effects Therapeutics. Pharmacology RM1-950 Tao Wang Linlin Cao Qikun Jiang Tianhong Zhang Topical Medication Therapy for Glaucoma and Ocular Hypertension
description	Glaucoma is one of the most common causes of blindness, thus seriously affecting people’s health and quality of life. The topical medical therapy is as the first line treatment in the management of glaucoma since it is inexpensive, convenient, effective, and safe. This review summarizes and compares extensive clinical trials on the topical medications for the treatment of glaucoma, including topical monotherapy agents, topical fixed-combination agents, topical non-fixed combination agents, and their composition, mechanism of action, efficacy, and adverse effects, which will provide reference for optimal choice of clinical medication. Fixed-combination therapeutics offer greater efficacy, reliable security, clinical compliance, and tolerance than non-fixed combination agents and monotherapy agents, which will become a prefer option for the treatment of glaucoma. Meanwhile, we also discuss new trends in the field of new fixed combinations of medications, which may better control IOP and treat glaucoma.
format	article
author	Tao Wang Linlin Cao Qikun Jiang Tianhong Zhang
author_facet	Tao Wang Linlin Cao Qikun Jiang Tianhong Zhang
author_sort	Tao Wang
title	Topical Medication Therapy for Glaucoma and Ocular Hypertension
title_short	Topical Medication Therapy for Glaucoma and Ocular Hypertension
title_full	Topical Medication Therapy for Glaucoma and Ocular Hypertension
title_fullStr	Topical Medication Therapy for Glaucoma and Ocular Hypertension
title_full_unstemmed	Topical Medication Therapy for Glaucoma and Ocular Hypertension
title_sort	topical medication therapy for glaucoma and ocular hypertension
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/9a431718bd274d4cab37383978bd6879
work_keys_str_mv	AT taowang topicalmedicationtherapyforglaucomaandocularhypertension AT linlincao topicalmedicationtherapyforglaucomaandocularhypertension AT qikunjiang topicalmedicationtherapyforglaucomaandocularhypertension AT tianhongzhang topicalmedicationtherapyforglaucomaandocularhypertension
_version_	1718403943797620736

Topical Medication Therapy for Glaucoma and Ocular Hypertension

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