Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities

Metabolic reprogramming originally referred to the ability of cancer cells to metabolically adapt to changes in environmental conditions to meet both energy consumption and proliferation requirements. According to recent studies, renal cells are also capable of reprogramming their metabolism after k...

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Autores principales: Yin Li, Zixin Sha, Hui Peng
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/9a4959b5e70640e2a7ea1e095584eeac
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spelling oai:doaj.org-article:9a4959b5e70640e2a7ea1e095584eeac2021-11-08T02:35:45ZMetabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities2090-215810.1155/2021/5497346https://doaj.org/article/9a4959b5e70640e2a7ea1e095584eeac2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/5497346https://doaj.org/toc/2090-2158Metabolic reprogramming originally referred to the ability of cancer cells to metabolically adapt to changes in environmental conditions to meet both energy consumption and proliferation requirements. According to recent studies, renal cells are also capable of reprogramming their metabolism after kidney injury, and these cells undergo different kinds of metabolic reprogramming in different kidney diseases. Metabolic reprogramming also plays a role in the progression and prognosis of kidney diseases. Therefore, metabolic reprogramming is not only a prominent feature but also an important contributor to the pathophysiology of kidney diseases. Here, we briefly review kidney diseases and metabolic reprogramming and discuss new ways to treat kidney diseases.Yin LiZixin ShaHui PengHindawi LimitedarticleDiseases of the genitourinary system. UrologyRC870-923ENInternational Journal of Nephrology, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the genitourinary system. Urology
RC870-923
spellingShingle Diseases of the genitourinary system. Urology
RC870-923
Yin Li
Zixin Sha
Hui Peng
Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
description Metabolic reprogramming originally referred to the ability of cancer cells to metabolically adapt to changes in environmental conditions to meet both energy consumption and proliferation requirements. According to recent studies, renal cells are also capable of reprogramming their metabolism after kidney injury, and these cells undergo different kinds of metabolic reprogramming in different kidney diseases. Metabolic reprogramming also plays a role in the progression and prognosis of kidney diseases. Therefore, metabolic reprogramming is not only a prominent feature but also an important contributor to the pathophysiology of kidney diseases. Here, we briefly review kidney diseases and metabolic reprogramming and discuss new ways to treat kidney diseases.
format article
author Yin Li
Zixin Sha
Hui Peng
author_facet Yin Li
Zixin Sha
Hui Peng
author_sort Yin Li
title Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
title_short Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
title_full Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
title_fullStr Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
title_full_unstemmed Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities
title_sort metabolic reprogramming in kidney diseases: evidence and therapeutic opportunities
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/9a4959b5e70640e2a7ea1e095584eeac
work_keys_str_mv AT yinli metabolicreprogramminginkidneydiseasesevidenceandtherapeuticopportunities
AT zixinsha metabolicreprogramminginkidneydiseasesevidenceandtherapeuticopportunities
AT huipeng metabolicreprogramminginkidneydiseasesevidenceandtherapeuticopportunities
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