The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study

Bingjun Yu, Nianshuang Li, Jiarong Li, Jianhua Wan, Wenhua He, Yin Zhu, Nonghua Lu Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, People’s Republic of ChinaCorrespondence: Nonghua LuDepartment of Gastroenterology, Th...

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Autores principales:	Yu B, Li N, Li J, Wan J, He W, Zhu Y, Lu N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	acute pancreatitis ageing patients clinical traits death rate icu admission rate Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/9a55fb51e85d44bf8c4474486736559f
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spelling	oai:doaj.org-article:9a55fb51e85d44bf8c4474486736559f2021-12-02T08:46:54ZThe Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study1178-1998https://doaj.org/article/9a55fb51e85d44bf8c4474486736559f2020-09-01T00:00:00Zhttps://www.dovepress.com/the-clinical-characteristics-of-acute-pancreatitis-in-gerontal-patient-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Bingjun Yu, Nianshuang Li, Jiarong Li, Jianhua Wan, Wenhua He, Yin Zhu, Nonghua Lu Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, People’s Republic of ChinaCorrespondence: Nonghua LuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, 17 Yong Waizheng Street, Donghu District, Nanchang 330006, Jiangxi Province, People’s Republic of ChinaEmail lunonghua@ncu.edu.cnBackground: The incidence of acute pancreatitis (AP) in ageing patients has increased in recent years, and results regarding the clinical outcomes of these patients are controversial. The aim of this study was to compare the clinical outcomes of AP in ageing patients over 60 years old.Methods: Eighty patients aged ≥ 80 years (oldest group) were compared to 393 patients aged 60 to 79 years (older group). The clinical course and biochemical and radiological data were evaluated. The primary endpoints were mortality rate, intensive care unit (ICU) admission rate and in-hospital length of stay (LOS). The secondary endpoints were the incidence of operative treatment and complications of AP.Results: Abdominal pain (61.3% vs 46.3%, P=0.013) was less common in the oldest group. Jaundice (17.5% vs 8.9%, P=0.021) and dyspnoea (26.3% vs 11.5%, P=0.001) were more obvious in the oldest group than in the older group. The mean BMI was lower in the oldest group than in the older group (21.07± 3.18 vs 22.36± 2.89, P = 0.001). Age over 80 years (P=0.011) and organ failure (P< 0.05) were independent risk factors for mortality. More severe AP (P=0.001), abdominal pain (P=0.033) and organ failure (P< 0.05) were associated with the ICU admission rate. Age over 80 years (P=0.001), more severe AP (P=0.001), female sex (P=0.018), jaundice (P=0.038), operative treatment (P< 0.05) and organ failure (P< 0.05) were risk factors for increased LOS.Conclusion: The oldest group had a higher death rate and longer LOS than the older group. More attention should be given to the clinical symptoms of this frail population. We propose that more comprehensive and goal-directed attendant diagnostic procedures should be performed to detect the disease early and to improve the outcomes of ageing patients.Keywords: acute pancreatitis, ageing patients, clinical traits, death rate, ICU admission rateYu BLi NLi JWan JHe WZhu YLu NDove Medical Pressarticleacute pancreatitisageing patientsclinical traitsdeath rateicu admission rateGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 15, Pp 1541-1553 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute pancreatitis ageing patients clinical traits death rate icu admission rate Geriatrics RC952-954.6
spellingShingle	acute pancreatitis ageing patients clinical traits death rate icu admission rate Geriatrics RC952-954.6 Yu B Li N Li J Wan J He W Zhu Y Lu N The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
description	Bingjun Yu, Nianshuang Li, Jiarong Li, Jianhua Wan, Wenhua He, Yin Zhu, Nonghua Lu Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, People’s Republic of ChinaCorrespondence: Nonghua LuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, 17 Yong Waizheng Street, Donghu District, Nanchang 330006, Jiangxi Province, People’s Republic of ChinaEmail lunonghua@ncu.edu.cnBackground: The incidence of acute pancreatitis (AP) in ageing patients has increased in recent years, and results regarding the clinical outcomes of these patients are controversial. The aim of this study was to compare the clinical outcomes of AP in ageing patients over 60 years old.Methods: Eighty patients aged ≥ 80 years (oldest group) were compared to 393 patients aged 60 to 79 years (older group). The clinical course and biochemical and radiological data were evaluated. The primary endpoints were mortality rate, intensive care unit (ICU) admission rate and in-hospital length of stay (LOS). The secondary endpoints were the incidence of operative treatment and complications of AP.Results: Abdominal pain (61.3% vs 46.3%, P=0.013) was less common in the oldest group. Jaundice (17.5% vs 8.9%, P=0.021) and dyspnoea (26.3% vs 11.5%, P=0.001) were more obvious in the oldest group than in the older group. The mean BMI was lower in the oldest group than in the older group (21.07± 3.18 vs 22.36± 2.89, P = 0.001). Age over 80 years (P=0.011) and organ failure (P< 0.05) were independent risk factors for mortality. More severe AP (P=0.001), abdominal pain (P=0.033) and organ failure (P< 0.05) were associated with the ICU admission rate. Age over 80 years (P=0.001), more severe AP (P=0.001), female sex (P=0.018), jaundice (P=0.038), operative treatment (P< 0.05) and organ failure (P< 0.05) were risk factors for increased LOS.Conclusion: The oldest group had a higher death rate and longer LOS than the older group. More attention should be given to the clinical symptoms of this frail population. We propose that more comprehensive and goal-directed attendant diagnostic procedures should be performed to detect the disease early and to improve the outcomes of ageing patients.Keywords: acute pancreatitis, ageing patients, clinical traits, death rate, ICU admission rate
format	article
author	Yu B Li N Li J Wan J He W Zhu Y Lu N
author_facet	Yu B Li N Li J Wan J He W Zhu Y Lu N
author_sort	Yu B
title	The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
title_short	The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
title_full	The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
title_fullStr	The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
title_full_unstemmed	The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study
title_sort	clinical characteristics of acute pancreatitis in gerontal patients: a retrospective study
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/9a55fb51e85d44bf8c4474486736559f
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The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study

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