Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice

Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner. The data suggests that neonatal mice are a promising model for further studies.

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Autores principales:	Alexa N. Roth, Emily W. Helm, Carmen Mirabelli, Erin Kirsche, Jonathan C. Smith, Laura B. Eurell, Sourish Ghosh, Nihal Altan-Bonnet, Christiane E. Wobus, Stephanie M. Karst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9a6932ec89e94268872ca25929c2bda7
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spelling	oai:doaj.org-article:9a6932ec89e94268872ca25929c2bda72021-12-02T14:58:18ZNorovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice10.1038/s41467-020-16798-12041-1723https://doaj.org/article/9a6932ec89e94268872ca25929c2bda72020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16798-1https://doaj.org/toc/2041-1723Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner. The data suggests that neonatal mice are a promising model for further studies.Alexa N. RothEmily W. HelmCarmen MirabelliErin KirscheJonathan C. SmithLaura B. EurellSourish GhoshNihal Altan-BonnetChristiane E. WobusStephanie M. KarstNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexa N. Roth Emily W. Helm Carmen Mirabelli Erin Kirsche Jonathan C. Smith Laura B. Eurell Sourish Ghosh Nihal Altan-Bonnet Christiane E. Wobus Stephanie M. Karst Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
description	Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner. The data suggests that neonatal mice are a promising model for further studies.
format	article
author	Alexa N. Roth Emily W. Helm Carmen Mirabelli Erin Kirsche Jonathan C. Smith Laura B. Eurell Sourish Ghosh Nihal Altan-Bonnet Christiane E. Wobus Stephanie M. Karst
author_facet	Alexa N. Roth Emily W. Helm Carmen Mirabelli Erin Kirsche Jonathan C. Smith Laura B. Eurell Sourish Ghosh Nihal Altan-Bonnet Christiane E. Wobus Stephanie M. Karst
author_sort	Alexa N. Roth
title	Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
title_short	Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
title_full	Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
title_fullStr	Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
title_full_unstemmed	Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
title_sort	norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/9a6932ec89e94268872ca25929c2bda7
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Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice

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