Staphylococcal Scalded Skin Syndrome and Bullous Impetigo

Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by <i>Staphylococcus aureus</i>. The pathogenesis of both conditions centers around exotoxin mediated cleavage of desmoglein-1, which results in intraepidermal desquamation. Bullous impetigo is due to...

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Autores principales:	Morgan Brazel, Anand Desai, Abhirup Are, Kiran Motaparthi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	staphylococcal scalded skin syndrome bullous impetigo <i>Staphylococcus aureus</i> Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9a6fb28e28384a338764fec27df67fd6
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spelling	oai:doaj.org-article:9a6fb28e28384a338764fec27df67fd62021-11-25T18:18:10ZStaphylococcal Scalded Skin Syndrome and Bullous Impetigo10.3390/medicina571111571648-91441010-660Xhttps://doaj.org/article/9a6fb28e28384a338764fec27df67fd62021-10-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1157https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by <i>Staphylococcus aureus</i>. The pathogenesis of both conditions centers around exotoxin mediated cleavage of desmoglein-1, which results in intraepidermal desquamation. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target <i>S. aureus.</i> These conditions can sometimes be confused with other conditions that result in superficial blistering; the distinguishing features are outlined below.Morgan BrazelAnand DesaiAbhirup AreKiran MotaparthiMDPI AGarticlestaphylococcal scalded skin syndromebullous impetigo<i>Staphylococcus aureus</i>Medicine (General)R5-920ENMedicina, Vol 57, Iss 1157, p 1157 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	staphylococcal scalded skin syndrome bullous impetigo <i>Staphylococcus aureus</i> Medicine (General) R5-920
spellingShingle	staphylococcal scalded skin syndrome bullous impetigo <i>Staphylococcus aureus</i> Medicine (General) R5-920 Morgan Brazel Anand Desai Abhirup Are Kiran Motaparthi Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
description	Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by <i>Staphylococcus aureus</i>. The pathogenesis of both conditions centers around exotoxin mediated cleavage of desmoglein-1, which results in intraepidermal desquamation. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target <i>S. aureus.</i> These conditions can sometimes be confused with other conditions that result in superficial blistering; the distinguishing features are outlined below.
format	article
author	Morgan Brazel Anand Desai Abhirup Are Kiran Motaparthi
author_facet	Morgan Brazel Anand Desai Abhirup Are Kiran Motaparthi
author_sort	Morgan Brazel
title	Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
title_short	Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
title_full	Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
title_fullStr	Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
title_full_unstemmed	Staphylococcal Scalded Skin Syndrome and Bullous Impetigo
title_sort	staphylococcal scalded skin syndrome and bullous impetigo
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9a6fb28e28384a338764fec27df67fd6
work_keys_str_mv	AT morganbrazel staphylococcalscaldedskinsyndromeandbullousimpetigo AT ananddesai staphylococcalscaldedskinsyndromeandbullousimpetigo AT abhirupare staphylococcalscaldedskinsyndromeandbullousimpetigo AT kiranmotaparthi staphylococcalscaldedskinsyndromeandbullousimpetigo
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Staphylococcal Scalded Skin Syndrome and Bullous Impetigo

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