Antiviral Therapeutic Potential of Curcumin: An Update

The treatment of viral disease has become a medical challenge because of the increasing incidence and prevalence of human viral pathogens, as well as the lack of viable treatment alternatives, including plant-derived strategies. This review attempts to investigate the trends of research on in vitro...

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Autores principales:	Abdollah Ardebili, Mohammad Hassan Pouriayevali, Sahar Aleshikh, Marziyeh Zahani, Mehdi Ajorloo, Ahdieh Izanloo, Abolghasem Siyadatpanah, Hadi Razavi Nikoo, Polrat Wilairatana, Henrique Douglas Melo Coutinho
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	antiviral agent curcumin herbs human viruses X Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/9a707df990c24f14a5b047ccefa19b41
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spelling	oai:doaj.org-article:9a707df990c24f14a5b047ccefa19b412021-11-25T18:29:01ZAntiviral Therapeutic Potential of Curcumin: An Update10.3390/molecules262269941420-3049https://doaj.org/article/9a707df990c24f14a5b047ccefa19b412021-11-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/22/6994https://doaj.org/toc/1420-3049The treatment of viral disease has become a medical challenge because of the increasing incidence and prevalence of human viral pathogens, as well as the lack of viable treatment alternatives, including plant-derived strategies. This review attempts to investigate the trends of research on in vitro antiviral effects of curcumin against different classes of human viral pathogens worldwide. Various electronic databases, including PubMed, Scopus, Web of Science, and Google Scholar were searched for published English articles evaluating the anti-viral activity of curcumin. Data were then extracted and analyzed. The forty-three studies (published from 1993 to 2020) that were identified contain data for 24 different viruses. The 50% cytotoxic concentration (CC50), 50% effective/inhibitory concentration (EC50/IC50), and stimulation index (SI) parameters showed that curcumin had antiviral activity against viruses causing diseases in humans. Data presented in this review highlight the potential antiviral applications of curcumin and open new avenues for further experiments on the clinical applications of curcumin and its derivatives.Abdollah ArdebiliMohammad Hassan PouriayevaliSahar AleshikhMarziyeh ZahaniMehdi AjorlooAhdieh IzanlooAbolghasem SiyadatpanahHadi Razavi NikooPolrat WilairatanaHenrique Douglas Melo CoutinhoMDPI AGarticleantiviral agentcurcuminherbshuman viruses XOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6994, p 6994 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antiviral agent curcumin herbs human viruses X Organic chemistry QD241-441
spellingShingle	antiviral agent curcumin herbs human viruses X Organic chemistry QD241-441 Abdollah Ardebili Mohammad Hassan Pouriayevali Sahar Aleshikh Marziyeh Zahani Mehdi Ajorloo Ahdieh Izanloo Abolghasem Siyadatpanah Hadi Razavi Nikoo Polrat Wilairatana Henrique Douglas Melo Coutinho Antiviral Therapeutic Potential of Curcumin: An Update
description	The treatment of viral disease has become a medical challenge because of the increasing incidence and prevalence of human viral pathogens, as well as the lack of viable treatment alternatives, including plant-derived strategies. This review attempts to investigate the trends of research on in vitro antiviral effects of curcumin against different classes of human viral pathogens worldwide. Various electronic databases, including PubMed, Scopus, Web of Science, and Google Scholar were searched for published English articles evaluating the anti-viral activity of curcumin. Data were then extracted and analyzed. The forty-three studies (published from 1993 to 2020) that were identified contain data for 24 different viruses. The 50% cytotoxic concentration (CC50), 50% effective/inhibitory concentration (EC50/IC50), and stimulation index (SI) parameters showed that curcumin had antiviral activity against viruses causing diseases in humans. Data presented in this review highlight the potential antiviral applications of curcumin and open new avenues for further experiments on the clinical applications of curcumin and its derivatives.
format	article
author	Abdollah Ardebili Mohammad Hassan Pouriayevali Sahar Aleshikh Marziyeh Zahani Mehdi Ajorloo Ahdieh Izanloo Abolghasem Siyadatpanah Hadi Razavi Nikoo Polrat Wilairatana Henrique Douglas Melo Coutinho
author_facet	Abdollah Ardebili Mohammad Hassan Pouriayevali Sahar Aleshikh Marziyeh Zahani Mehdi Ajorloo Ahdieh Izanloo Abolghasem Siyadatpanah Hadi Razavi Nikoo Polrat Wilairatana Henrique Douglas Melo Coutinho
author_sort	Abdollah Ardebili
title	Antiviral Therapeutic Potential of Curcumin: An Update
title_short	Antiviral Therapeutic Potential of Curcumin: An Update
title_full	Antiviral Therapeutic Potential of Curcumin: An Update
title_fullStr	Antiviral Therapeutic Potential of Curcumin: An Update
title_full_unstemmed	Antiviral Therapeutic Potential of Curcumin: An Update
title_sort	antiviral therapeutic potential of curcumin: an update
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9a707df990c24f14a5b047ccefa19b41
work_keys_str_mv	AT abdollahardebili antiviraltherapeuticpotentialofcurcuminanupdate AT mohammadhassanpouriayevali antiviraltherapeuticpotentialofcurcuminanupdate AT saharaleshikh antiviraltherapeuticpotentialofcurcuminanupdate AT marziyehzahani antiviraltherapeuticpotentialofcurcuminanupdate AT mehdiajorloo antiviraltherapeuticpotentialofcurcuminanupdate AT ahdiehizanloo antiviraltherapeuticpotentialofcurcuminanupdate AT abolghasemsiyadatpanah antiviraltherapeuticpotentialofcurcuminanupdate AT hadirazavinikoo antiviraltherapeuticpotentialofcurcuminanupdate AT polratwilairatana antiviraltherapeuticpotentialofcurcuminanupdate AT henriquedouglasmelocoutinho antiviraltherapeuticpotentialofcurcuminanupdate
_version_	1718411093219475456

Antiviral Therapeutic Potential of Curcumin: An Update

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