A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines

Microtubule-associated protein 6 (MAP6) is known to be important for synaptic plasticity and cognition, supposedly via interaction with microtubules. Here, the authors found that MAP6 is crucial for the stabilisation of enlarged synapses through its association with a different cytoskeletal element,...

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Autores principales: Leticia Peris, Mariano Bisbal, José Martinez-Hernandez, Yasmina Saoudi, Julie Jonckheere, Marta Rolland, Muriel Sebastien, Jacques Brocard, Eric Denarier, Christophe Bosc, Christophe Guerin, Sylvie Gory-Fauré, Jean Christophe Deloulme, Fabien Lanté, Isabelle Arnal, Alain Buisson, Yves Goldberg, Laurent Blanchoin, Christian Delphin, Annie Andrieux
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9a70b96ea1e0471499f443604529b0ce
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spelling oai:doaj.org-article:9a70b96ea1e0471499f443604529b0ce2021-12-02T14:39:04ZA key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines10.1038/s41467-018-05869-z2041-1723https://doaj.org/article/9a70b96ea1e0471499f443604529b0ce2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05869-zhttps://doaj.org/toc/2041-1723Microtubule-associated protein 6 (MAP6) is known to be important for synaptic plasticity and cognition, supposedly via interaction with microtubules. Here, the authors found that MAP6 is crucial for the stabilisation of enlarged synapses through its association with a different cytoskeletal element, actin.Leticia PerisMariano BisbalJosé Martinez-HernandezYasmina SaoudiJulie JonckheereMarta RollandMuriel SebastienJacques BrocardEric DenarierChristophe BoscChristophe GuerinSylvie Gory-FauréJean Christophe DeloulmeFabien LantéIsabelle ArnalAlain BuissonYves GoldbergLaurent BlanchoinChristian DelphinAnnie AndrieuxNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Leticia Peris
Mariano Bisbal
José Martinez-Hernandez
Yasmina Saoudi
Julie Jonckheere
Marta Rolland
Muriel Sebastien
Jacques Brocard
Eric Denarier
Christophe Bosc
Christophe Guerin
Sylvie Gory-Fauré
Jean Christophe Deloulme
Fabien Lanté
Isabelle Arnal
Alain Buisson
Yves Goldberg
Laurent Blanchoin
Christian Delphin
Annie Andrieux
A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
description Microtubule-associated protein 6 (MAP6) is known to be important for synaptic plasticity and cognition, supposedly via interaction with microtubules. Here, the authors found that MAP6 is crucial for the stabilisation of enlarged synapses through its association with a different cytoskeletal element, actin.
format article
author Leticia Peris
Mariano Bisbal
José Martinez-Hernandez
Yasmina Saoudi
Julie Jonckheere
Marta Rolland
Muriel Sebastien
Jacques Brocard
Eric Denarier
Christophe Bosc
Christophe Guerin
Sylvie Gory-Fauré
Jean Christophe Deloulme
Fabien Lanté
Isabelle Arnal
Alain Buisson
Yves Goldberg
Laurent Blanchoin
Christian Delphin
Annie Andrieux
author_facet Leticia Peris
Mariano Bisbal
José Martinez-Hernandez
Yasmina Saoudi
Julie Jonckheere
Marta Rolland
Muriel Sebastien
Jacques Brocard
Eric Denarier
Christophe Bosc
Christophe Guerin
Sylvie Gory-Fauré
Jean Christophe Deloulme
Fabien Lanté
Isabelle Arnal
Alain Buisson
Yves Goldberg
Laurent Blanchoin
Christian Delphin
Annie Andrieux
author_sort Leticia Peris
title A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
title_short A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
title_full A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
title_fullStr A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
title_full_unstemmed A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
title_sort key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9a70b96ea1e0471499f443604529b0ce
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