Oxidative 1,2-carboamination of alkenes with alkyl nitriles and amines toward γ-amino alkyl nitriles

Difunctionalization of readily available alkenes is a powerful method to quickly build molecular complexity. Here the authors report a three-component, oxidative carboamination between alkenes, alkyl nitriles and amines, producingγ-amino alkyl nitriles.

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Detalles Bibliográficos
Autores principales: Yan-Yun Liu, Xu-Heng Yang, Ren-Jie Song, Shenglian Luo, Jin-Heng Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9a71d33a9b5d424e89d384f5067e6a5e
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Descripción
Sumario:Difunctionalization of readily available alkenes is a powerful method to quickly build molecular complexity. Here the authors report a three-component, oxidative carboamination between alkenes, alkyl nitriles and amines, producingγ-amino alkyl nitriles.