Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease.

Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease.

Recent studies in animal models of Alzheimer's disease (AD) show that amyloid-beta (Aβ) misfolding can be transmissible; however, the mechanisms by which this process occurs have not been fully explored. The goal of this study was to analyze whether depletion of aggregates from an AD brain supp...

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Autores principales: Claudia Duran-Aniotz, Rodrigo Morales, Ines Moreno-Gonzalez, Ping Ping Hu, Joseph Fedynyshyn, Claudio Soto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9a7e6cd0f02841ca81b6223878587884
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