Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease

Toshiyuki Oshitari1, Jiro Yotsukura1, Kaoru Asahagi1, Takayuki Baba1, Takashi Kishimoto2, Shuichi Yamamoto11Department of Ophthalmology and Visual Science, 2Department of Molecular Pathology, Chiba University Graduate School of Medicine, Chiba, JapanAbstract: The purpose of this study is to present...

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Autores principales:	Toshiyuki Oshitari, Jiro Yotsukura, Kaoru Asahagi, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9a80410b013148fb9794b1dcea160877
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spelling	oai:doaj.org-article:9a80410b013148fb9794b1dcea1608772021-12-02T03:09:35ZRelationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease1177-54671177-5483https://doaj.org/article/9a80410b013148fb9794b1dcea1608772010-12-01T00:00:00Zhttp://www.dovepress.com/relationship-between-chronic-sclerosing-dacryoadenitis-with-high-level-a5986https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Toshiyuki Oshitari1, Jiro Yotsukura1, Kaoru Asahagi1, Takayuki Baba1, Takashi Kishimoto2, Shuichi Yamamoto11Department of Ophthalmology and Visual Science, 2Department of Molecular Pathology, Chiba University Graduate School of Medicine, Chiba, JapanAbstract: The purpose of this study is to present a case of chronic sclerosing dacryoadenitis with high level of IgG4 in a patient diagnosed earlier with Castleman disease. A 79-year-old man noticed a swelling of his lower left jaw that was first seen 8 years earlier. He was diagnosed with Castleman disease from the histopathological examination of a biopsy of the submandibular gland. Since then, the size of the gland had not changed, and he had no systemic inflammatory signs or symptoms. He developed diplopia a year earlier, and CT scans showed bilateral swelling of the lacrimal glands. He was referred to our hospital for further examinations. The patient underwent partial dacryoadenectomy. From the histopathological examinations, he was diagnosed with chronic sclerosing dacryoadenitis with high level of the serum IgG4. He underwent oral steroid therapy and the swollen lacrimal glands were significantly improved. The results suggest that there may be pathological links between IgG4-related dacryoadenitis and Castleman disease.Keywords: IgG4, dacryoadenitis, Castleman disease, steroid Toshiyuki OshitariJiro YotsukuraKaoru Asahagiet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 23-25 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Toshiyuki Oshitari Jiro Yotsukura Kaoru Asahagi et al Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
description	Toshiyuki Oshitari1, Jiro Yotsukura1, Kaoru Asahagi1, Takayuki Baba1, Takashi Kishimoto2, Shuichi Yamamoto11Department of Ophthalmology and Visual Science, 2Department of Molecular Pathology, Chiba University Graduate School of Medicine, Chiba, JapanAbstract: The purpose of this study is to present a case of chronic sclerosing dacryoadenitis with high level of IgG4 in a patient diagnosed earlier with Castleman disease. A 79-year-old man noticed a swelling of his lower left jaw that was first seen 8 years earlier. He was diagnosed with Castleman disease from the histopathological examination of a biopsy of the submandibular gland. Since then, the size of the gland had not changed, and he had no systemic inflammatory signs or symptoms. He developed diplopia a year earlier, and CT scans showed bilateral swelling of the lacrimal glands. He was referred to our hospital for further examinations. The patient underwent partial dacryoadenectomy. From the histopathological examinations, he was diagnosed with chronic sclerosing dacryoadenitis with high level of the serum IgG4. He underwent oral steroid therapy and the swollen lacrimal glands were significantly improved. The results suggest that there may be pathological links between IgG4-related dacryoadenitis and Castleman disease.Keywords: IgG4, dacryoadenitis, Castleman disease, steroid
format	article
author	Toshiyuki Oshitari Jiro Yotsukura Kaoru Asahagi et al
author_facet	Toshiyuki Oshitari Jiro Yotsukura Kaoru Asahagi et al
author_sort	Toshiyuki Oshitari
title	Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
title_short	Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
title_full	Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
title_fullStr	Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
title_full_unstemmed	Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease
title_sort	relationship between chronic sclerosing dacryoadenitis with high level of igg4 and castleman disease
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/9a80410b013148fb9794b1dcea160877
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Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease

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