Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231

Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231

Abstract Introduction Studies using different assays and technologies showed highly promising diagnostic value of plasma phosphorylated (P-)tau levels for Alzheimer’s disease (AD). We aimed to compare six P-tau Simoa assays, including three P-tau181 (Eli Lilly, ADx, Quanterix), one P-tau217 (Eli Lil...

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Main Authors: Sherif Bayoumy, Inge M. W. Verberk, Ben den Dulk, Zulaiga Hussainali, Marissa Zwan, Wiesje M. van der Flier, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Jeffrey L. Dage, Charlotte E. Teunissen
Format: article
Language:EN
Published: BMC 2021
Subjects:
Alzheimer’s disease
Blood biomarkers
P-tau181
P-tau217
P-tau231
Phosphorylated tau proteins
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/9a80f98ef3db432c84a8599a0bf54390
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https://doaj.org/article/9a80f98ef3db432c84a8599a0bf54390

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