Quantification of differential gene expression by multiplexed targeted resequencing of cDNA

Transcriptome sequencing is a powerful tool for functional analysis of different types of RNA molecules in a wide range of applications. Here the authors use targeted resequencing of cDNA with single-molecule molecular inversion probes as a cost-effective, high-throughput tool for mRNA quantificatio...

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Autores principales: Peer Arts, Jori van der Raadt, Sebastianus H.C. van Gestel, Marloes Steehouwer, Jay Shendure, Alexander Hoischen, Cornelis A. Albers
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9a823940d12b4dcf8e3e20dd307ee268
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Sumario:Transcriptome sequencing is a powerful tool for functional analysis of different types of RNA molecules in a wide range of applications. Here the authors use targeted resequencing of cDNA with single-molecule molecular inversion probes as a cost-effective, high-throughput tool for mRNA quantification.