Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells

Eukaryotic organisms are continuously exposed to bacteriophages, but these are not thought to enter non-phagocytic cells. Here, Lehti et al. show that a bacteriophage can bind to a specific receptor on the surface of human neuroblastoma cells in vitro, and be internalized via the endolysosomal route...

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Autores principales:	Timo A. Lehti, Maria I. Pajunen, Maria S. Skog, Jukka Finne
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9a861fc04cc948d58d4f704dd1c2cac9
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spelling	oai:doaj.org-article:9a861fc04cc948d58d4f704dd1c2cac92021-12-02T14:40:47ZInternalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells10.1038/s41467-017-02057-32041-1723https://doaj.org/article/9a861fc04cc948d58d4f704dd1c2cac92017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02057-3https://doaj.org/toc/2041-1723Eukaryotic organisms are continuously exposed to bacteriophages, but these are not thought to enter non-phagocytic cells. Here, Lehti et al. show that a bacteriophage can bind to a specific receptor on the surface of human neuroblastoma cells in vitro, and be internalized via the endolysosomal route.Timo A. LehtiMaria I. PajunenMaria S. SkogJukka FinneNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timo A. Lehti Maria I. Pajunen Maria S. Skog Jukka Finne Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
description	Eukaryotic organisms are continuously exposed to bacteriophages, but these are not thought to enter non-phagocytic cells. Here, Lehti et al. show that a bacteriophage can bind to a specific receptor on the surface of human neuroblastoma cells in vitro, and be internalized via the endolysosomal route.
format	article
author	Timo A. Lehti Maria I. Pajunen Maria S. Skog Jukka Finne
author_facet	Timo A. Lehti Maria I. Pajunen Maria S. Skog Jukka Finne
author_sort	Timo A. Lehti
title	Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
title_short	Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
title_full	Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
title_fullStr	Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
title_full_unstemmed	Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
title_sort	internalization of a polysialic acid-binding escherichia coli bacteriophage into eukaryotic neuroblastoma cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9a861fc04cc948d58d4f704dd1c2cac9
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Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells

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