Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.
Guardado en:
Autores principales: | Danhua Zhang, Keith P. Gates, Lindsey Barske, Guangliang Wang, Joseph J. Lancman, Xin-Xin I. Zeng, Megan Groff, Kasper Wang, Michael J. Parsons, J. Gage Crump, P. Duc Si Dong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/9a869d75f80549c8a2ff75e1bc7269a8 |
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