Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Several inhibitors of the electron transport chain (ETC) are active against Mycobacterium tuberculosis. Here, Lamprecht et al. show that a combination of known inhibitors (bedaquiline, Q203 and clofazimine) displays synergistic effects on the M. tuberculosis ETC and improved antibacterial activity i...

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Autores principales: Dirk A. Lamprecht, Peter M. Finin, Md. Aejazur Rahman, Bridgette M. Cumming, Shannon L. Russell, Surendranadha R. Jonnala, John H. Adamson, Adrie J. C. Steyn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9a86dfe38a8246cd9d09bf2f836eeae4
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