Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation

Chromosome instability frequently occurs due to issues with chromosome-microtubule attachments. Here the authors show that the Astrin-PP1 and Cyclin-B-CDK1 pathways counteract each other to protect chromosome-microtubule attachments independent of biorientation.

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Autores principales:	Xinhong Song, Duccio Conti, Roshan L. Shrestha, Dominique Braun, Viji M. Draviam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9a8bb329ba4246098107250f4606529c
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spelling	oai:doaj.org-article:9a8bb329ba4246098107250f4606529c2021-12-05T12:22:20ZCounteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation10.1038/s41467-021-27131-92041-1723https://doaj.org/article/9a8bb329ba4246098107250f4606529c2021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27131-9https://doaj.org/toc/2041-1723Chromosome instability frequently occurs due to issues with chromosome-microtubule attachments. Here the authors show that the Astrin-PP1 and Cyclin-B-CDK1 pathways counteract each other to protect chromosome-microtubule attachments independent of biorientation.Xinhong SongDuccio ContiRoshan L. ShresthaDominique BraunViji M. DraviamNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xinhong Song Duccio Conti Roshan L. Shrestha Dominique Braun Viji M. Draviam Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
description	Chromosome instability frequently occurs due to issues with chromosome-microtubule attachments. Here the authors show that the Astrin-PP1 and Cyclin-B-CDK1 pathways counteract each other to protect chromosome-microtubule attachments independent of biorientation.
format	article
author	Xinhong Song Duccio Conti Roshan L. Shrestha Dominique Braun Viji M. Draviam
author_facet	Xinhong Song Duccio Conti Roshan L. Shrestha Dominique Braun Viji M. Draviam
author_sort	Xinhong Song
title	Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
title_short	Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
title_full	Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
title_fullStr	Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
title_full_unstemmed	Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
title_sort	counteraction between astrin-pp1 and cyclin-b-cdk1 pathways protects chromosome-microtubule attachments independent of biorientation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9a8bb329ba4246098107250f4606529c
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Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation

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