Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas

Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas

Somatic cell nuclear transfer (SCNT) frequently results in abnormal placenta development in cloned mice. Here the authors show that loss of histone methylation (H3K27me3) imprinting in clustered Sfmbt2 miRNAs contributes to SCNT placenta defect.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kimiko Inoue, Narumi Ogonuki, Satoshi Kamimura, Hiroki Inoue, Shogo Matoba, Michiko Hirose, Arata Honda, Kento Miura, Masashi Hada, Ayumi Hasegawa, Naomi Watanabe, Yukiko Dodo, Keiji Mochida, Atsuo Ogura
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/9a90abcae67c4e6d8be26b81b3d9af93
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/9a90abcae67c4e6d8be26b81b3d9af93

Documents similaires