Characterization of the nuclear and cytosolic transcriptomes in human brain tissue reveals new insights into the subcellular distribution of RNA transcripts
Abstract Transcriptome analysis has mainly relied on analyzing RNA sequencing data from whole cells, overlooking the impact of subcellular RNA localization and its influence on our understanding of gene function, and interpretation of gene expression signatures in cells. Here, we separated cytosolic...
Guardado en:
Autores principales: | Ammar Zaghlool, Adnan Niazi, Åsa K. Björklund, Jakub Orzechowski Westholm, Adam Ameur, Lars Feuk |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9a91b169ba164e37b3d0b15f348a8368 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The subcellular localization of bHLH transcription factor TCF4 is mediated by multiple nuclear localization and nuclear export signals
por: Beata Greb-Markiewicz, et al.
Publicado: (2019) -
The histone demethylase activity of Rph1 is not essential for its role in the transcriptional response to nutrient signaling.
por: Niklas Nordberg, et al.
Publicado: (2014) -
Rational Design of a Protein Kinase A Nuclear-cytosol Translocation Reporter
por: Allen K. Kim, et al.
Publicado: (2020) -
Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells.
por: Jakub Orzechowski Westholm, et al.
Publicado: (2012) -
Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K
por: Yong suk Cho, et al.
Publicado: (2018)